A prognostic model for estimating the time to virologic failure in HIV-1 infected patients undergoing a new combination antiretroviral therapy regimen

Simona Di Giambenedetto, Maria Luisa Di Pietro, Iuri Fanti, Andrea De Luca, Mcf Prosperi, G Meini, B Bruzzone, A Callegaro, G Penco, P Bagnarelli, V Micheli, E Paolini, A Di Biagio, V Ghisetti, M Zazzi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

9 Citazioni (Scopus)

Abstract

HIV-1 genotypic susceptibility scores (GSSs) were proven to be significant prognostic factors of fixed time-point virologic outcomes after combination antiretroviral therapy (cART) switch/initiation. However, their relative-hazard for the time to virologic failure has not been thoroughly investigated, and an expert system that is able to predict how long a new cART regimen will remain effective has never been designed.
Lingua originaleEnglish
pagine (da-a)40-40
Numero di pagine1
RivistaBMC Medical Informatics and Decision Making
Volume11
DOI
Stato di pubblicazionePubblicato - 2011

Keywords

  • Adult
  • Anti-HIV Agents
  • Cohort Studies
  • Drug Therapy, Combination
  • Female
  • HIV Infections
  • HIV-1
  • Humans
  • Male
  • Middle Aged
  • Proportional Hazards Models
  • Treatment Failure
  • Viral Load

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