A model of the pulsatile fluid flow in the lymph node

Giulia Giantesio; Alberto Girelli; Alessandro Musesti

doi:10.1016/j.mechrescom.2021.103743

A model of the pulsatile fluid flow in the lymph node

Giulia Giantesio
, Alberto Girelli
, Alessandro Musesti^*

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo › peer review

Abstract

The aim of the paper is to propose a mathematical model for the flow of the interstitial fluid in a lymph node, which main feature is the presence of a porous bulk region with a very low permeability, surrounded by a thin channel where the fluid can flow freely. The flow is driven by a pulsatile pressure gradient. An explicit solution is found in the case of a laminar flow in a simplified situation, while some finite element simulations are presented in a more realistic geometry.

Lingua originale	Inglese
pagine (da-a)	103743-N/A
Numero di pagine	6
Rivista	Mechanics Research Communications
Volume	116
Numero di pubblicazione	N/A
DOI	https://doi.org/10.1016/j.mechrescom.2021.103743
Stato di pubblicazione	Pubblicato - 2021

All Science Journal Classification (ASJC) codes

Ingegneria Civile e Strutturale
Scienza dei Materiali Generale
Fisica della Materia Condensata
Meccanica dei Materiali
Ingegneria Meccanica

Keywords

Darcy–Brinkman equation
Lymph node
Pulsatile flow

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10.1016/j.mechrescom.2021.103743

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author = "Giulia Giantesio and Alberto Girelli and Alessandro Musesti",

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AU - Giantesio, Giulia

AU - Girelli, Alberto

AU - Musesti, Alessandro

PY - 2021

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N2 - The aim of the paper is to propose a mathematical model for the flow of the interstitial fluid in a lymph node, which main feature is the presence of a porous bulk region with a very low permeability, surrounded by a thin channel where the fluid can flow freely. The flow is driven by a pulsatile pressure gradient. An explicit solution is found in the case of a laminar flow in a simplified situation, while some finite element simulations are presented in a more realistic geometry.

AB - The aim of the paper is to propose a mathematical model for the flow of the interstitial fluid in a lymph node, which main feature is the presence of a porous bulk region with a very low permeability, surrounded by a thin channel where the fluid can flow freely. The flow is driven by a pulsatile pressure gradient. An explicit solution is found in the case of a laminar flow in a simplified situation, while some finite element simulations are presented in a more realistic geometry.

KW - Darcy–Brinkman equation

KW - Lymph node

KW - Pulsatile flow

KW - Darcy–Brinkman equation

KW - Lymph node

KW - Pulsatile flow

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JF - Mechanics Research Communications

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A model of the pulsatile fluid flow in the lymph node

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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