A genetic study of neostriatal cholinergic neurones in C57BL/6 and DBA/2 mice

Risultato della ricerca: Contributo in rivistaArticolo in rivista

6 Citazioni (Scopus)

Abstract

In the present study Butcher's pharmaco-histochemical technique for acetylcholinesterase has been employed for a morphometrical analysis of striatal cholinergic neurones in crossbred C57BL/6 x DBA/2 F1 mice. The general organization of neostriatal cholinergic systems in hybrid mice was similar to that of parent strains. However, as shown by morphometry, the size of neostriatum in hybrids was larger than that of both parental strains, and the density of striatal cholinergic neurones was significantly lower than that of DBA/2 mice, being close to that of the C57BL/6 strain. The present data indicate that a reduced number of striatal cholinergic neurones is inherited as a dominant trait by these hybrid mice.
Lingua originaleEnglish
pagine (da-a)273-279
Numero di pagine7
RivistaFunctional Neurology
Volume2
Stato di pubblicazionePubblicato - 1987

Keywords

  • Acetylcholinesterase
  • Animals
  • Cell Count
  • Cholinergic Fibers
  • Corpus Striatum
  • Histocytochemistry
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, Inbred DBA

Fingerprint Entra nei temi di ricerca di 'A genetic study of neostriatal cholinergic neurones in C57BL/6 and DBA/2 mice'. Insieme formano una fingerprint unica.

Cita questo