A critical overview on ticagrelor in acute coronary syndromes

E. P. Navarese; Antonino Maria Tommaso Buffon; M. Kozinski; K. Obonska; M. Rychter; V. Kunadian; D. Austin; S. De Servi; A. Sukiennik; J. Kubica

doi:10.1093/qjmed/hcs187

A critical overview on ticagrelor in acute coronary syndromes

E. P. Navarese, Antonino Maria Tommaso Buffon, M. Kozinski, K. Obonska, M. Rychter, V. Kunadian, D. Austin, S. De Servi, A. Sukiennik, J. Kubica

Risultato della ricerca: Contributo in rivista › Articolo in rivista

13 Citazioni (Scopus)

Abstract

Until a few years ago, the mainstay of anti-platelet therapy in patients with acute coronary syndrome (ACS) was the combination of aspirin and clopidogrel, a P2Y12 receptor inhibitor. However, current clinical practice has now changed with the introduction of ticagrelor, a more potent cardiovascular drug than clopidogrel, without the limitations related to clopidogrel therapy. In this review, we provide a critical overview of ticagrelor in ACS, highlight the results with ticagrelor in several subgroups of patients and discuss the future trials.

Lingua originale	English
pagine (da-a)	105-115
Numero di pagine	11
Rivista	QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
Volume	106
DOI	https://doi.org/10.1093/qjmed/hcs187
Stato di pubblicazione	Pubblicato - 2013

Keywords

Acute Coronary Syndrome
Adenosine
Aspirin
Double-Blind Method
Female
Humans
Male
Platelet Aggregation Inhibitors
Purinergic P2 Receptor Antagonists
Randomized Controlled Trials as Topic
Risk Assessment
Ticlopidine
Treatment Outcome

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10.1093/qjmed/hcs187

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AU - Navarese, E. P.

AU - Buffon, Antonino Maria Tommaso

AU - Kozinski, M.

AU - Obonska, K.

AU - Rychter, M.

AU - Kunadian, V.

AU - Austin, D.

AU - De Servi, S.

AU - Sukiennik, A.

AU - Kubica, J.

PY - 2013

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AB - Until a few years ago, the mainstay of anti-platelet therapy in patients with acute coronary syndrome (ACS) was the combination of aspirin and clopidogrel, a P2Y12 receptor inhibitor. However, current clinical practice has now changed with the introduction of ticagrelor, a more potent cardiovascular drug than clopidogrel, without the limitations related to clopidogrel therapy. In this review, we provide a critical overview of ticagrelor in ACS, highlight the results with ticagrelor in several subgroups of patients and discuss the future trials.

KW - Acute Coronary Syndrome

KW - Adenosine

KW - Aspirin

KW - Double-Blind Method

KW - Female

KW - Humans

KW - Male

KW - Platelet Aggregation Inhibitors

KW - Purinergic P2 Receptor Antagonists

KW - Randomized Controlled Trials as Topic

KW - Risk Assessment

KW - Ticlopidine

KW - Treatment Outcome

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KW - Aspirin

KW - Double-Blind Method

KW - Female

KW - Humans

KW - Male

KW - Platelet Aggregation Inhibitors

KW - Purinergic P2 Receptor Antagonists

KW - Randomized Controlled Trials as Topic

KW - Risk Assessment

KW - Ticlopidine

KW - Treatment Outcome

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DO - 10.1093/qjmed/hcs187

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JF - QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

ER -

A critical overview on ticagrelor in acute coronary syndromes

Abstract

Keywords

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