A complete pathological response to treatment in a young patient with locally advanced minimal deviation adenocarcinoma of the uterine cervix undergoing chemoradiation followed by radical surgery

Maria Gabriella Ferrandina, Arnaldo Carbone, Gabriella Macchia, Marco Petrillo, Alessandro Lucidi, Alessio Giuseppe Morganti

Risultato della ricerca: Contributo in rivistaArticolo in rivista

1 Citazioni (Scopus)

Abstract

Minimal deviation adenocarcinoma (MDA) is a very rare variant of cervical adenocarcinoma. This pathological entity is composed of mucinous very-well-differentiated glands deeply invading cervical stroma, and often surrounded by a desmoplastic reaction. Despite its benign histological appearance, MDA is typically characterized by aggressive clinical behavior and by relevant difficulties in achieving a final diagnosis. Moreover, the intrinsic chemotherapy resistance, as well as the frequent failure of radiotherapy approaches has raised the need to investigate the efficacy of multimodal strategies for the treatment of MDA patients. Here, we report a case of locally advanced MDA of the uterine cervix in a very young woman, who was successfully treated with concomitant chemoradiation followed by radical surgery.
Lingua originaleEnglish
pagine (da-a)141-144
Numero di pagine4
RivistaGynecologic and Obstetric Investigation
Volume72
DOI
Stato di pubblicazionePubblicato - 2011

Keywords

  • Adenocarcinoma
  • Adult
  • Chemotherapy, Adjuvant
  • Combined Modality Therapy
  • Diagnosis, Differential
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Radiotherapy, Adjuvant
  • Uterine Cervical Neoplasms

Fingerprint Entra nei temi di ricerca di 'A complete pathological response to treatment in a young patient with locally advanced minimal deviation adenocarcinoma of the uterine cervix undergoing chemoradiation followed by radical surgery'. Insieme formano una fingerprint unica.

Cita questo