A Case of Insulinoma Detected by 68Ga-DOTANOC PET/CT and Missed by 18F-Dihydroxyphenylalanine PET/CT

Giorgio Treglia; Frediano Inzani; N Campanini; Guido Rindi; Salvatore Agnes; Alessandro Giordano; Vittoria Rufini

doi:10.1097/RLU.0b013e31825b222f

A Case of Insulinoma Detected by 68Ga-DOTANOC PET/CT and Missed by 18F-Dihydroxyphenylalanine PET/CT

Giorgio Treglia^*
, Frediano Inzani
, N Campanini
, Guido Rindi
, Salvatore Agnes
, Alessandro Giordano
, Vittoria Rufini

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo

14 Citazioni (Scopus)

Abstract

ABSTRACT: A 65-year-old woman with suspected insulinoma on the basis of clinical, biochemical, and conventional imaging data underwent F-dihydroxyphenylalanine (DOPA) PET/CT and Ga-DOTANOC PET/CT. F-DOPA PET/CT did not show any focal uptake in the pancreas, whereas Ga-DOTANOC PET/CT showed a focal area of intense uptake in the pancreatic tail. The patient underwent surgery and an insulinoma of about 20 mm in diameter was detected in the pancreatic tail. F-DOPA PET may fail in localizing insulin secreting tumors in adults; in these cases, the use of Ga-somatostatin analogs may lead to the correct diagnosis.

Lingua originale	Inglese
pagine (da-a)	267-270
Numero di pagine	4
Rivista	Clinical Nuclear Medicine
Numero di pubblicazione	N/A
DOI	https://doi.org/10.1097/RLU.0b013e31825b222f
Stato di pubblicazione	Pubblicato - 2013

All Science Journal Classification (ASJC) codes

Radiologia, Medicina Nucleare e Diagnostica per Immagini

Keywords

Insulinoma Imaging PET/CT

Accesso al documento

10.1097/RLU.0b013e31825b222f

Altri file e collegamenti

Cita questo

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AU - Treglia, Giorgio

AU - Inzani, Frediano

AU - Campanini, N

AU - Rindi, Guido

AU - Agnes, Salvatore

AU - Giordano, Alessandro

AU - Rufini, Vittoria

PY - 2013

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N2 - ABSTRACT: A 65-year-old woman with suspected insulinoma on the basis of clinical, biochemical, and conventional imaging data underwent F-dihydroxyphenylalanine (DOPA) PET/CT and Ga-DOTANOC PET/CT. F-DOPA PET/CT did not show any focal uptake in the pancreas, whereas Ga-DOTANOC PET/CT showed a focal area of intense uptake in the pancreatic tail. The patient underwent surgery and an insulinoma of about 20 mm in diameter was detected in the pancreatic tail. F-DOPA PET may fail in localizing insulin secreting tumors in adults; in these cases, the use of Ga-somatostatin analogs may lead to the correct diagnosis.

AB - ABSTRACT: A 65-year-old woman with suspected insulinoma on the basis of clinical, biochemical, and conventional imaging data underwent F-dihydroxyphenylalanine (DOPA) PET/CT and Ga-DOTANOC PET/CT. F-DOPA PET/CT did not show any focal uptake in the pancreas, whereas Ga-DOTANOC PET/CT showed a focal area of intense uptake in the pancreatic tail. The patient underwent surgery and an insulinoma of about 20 mm in diameter was detected in the pancreatic tail. F-DOPA PET may fail in localizing insulin secreting tumors in adults; in these cases, the use of Ga-somatostatin analogs may lead to the correct diagnosis.

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A Case of Insulinoma Detected by 68Ga-DOTANOC PET/CT and Missed by 18F-Dihydroxyphenylalanine PET/CT

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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