A Case of Insulinoma Detected by 68Ga-DOTANOC PET/CT and Missed by 18F-Dihydroxyphenylalanine PET/CT

Guido Rindi; Salvatore Agnes; Alessandro Giordano; Vittoria Rufini; Giorgio Treglia; Frediano Inzani; Nicoletta Campanini

doi:10.1097/RLU.0b013e31825b222f

A Case of Insulinoma Detected by 68Ga-DOTANOC PET/CT and Missed by 18F-Dihydroxyphenylalanine PET/CT

Guido Rindi, Salvatore Agnes, Alessandro Giordano, Vittoria Rufini, Giorgio Treglia, Frediano Inzani, Nicoletta Campanini

Risultato della ricerca: Contributo in rivista › Articolo in rivista

14 Citazioni (Scopus)

Abstract

ABSTRACT: A 65-year-old woman with suspected insulinoma on the basis of clinical, biochemical, and conventional imaging data underwent F-dihydroxyphenylalanine (DOPA) PET/CT and Ga-DOTANOC PET/CT. F-DOPA PET/CT did not show any focal uptake in the pancreas, whereas Ga-DOTANOC PET/CT showed a focal area of intense uptake in the pancreatic tail. The patient underwent surgery and an insulinoma of about 20 mm in diameter was detected in the pancreatic tail. F-DOPA PET may fail in localizing insulin secreting tumors in adults; in these cases, the use of Ga-somatostatin analogs may lead to the correct diagnosis.

Lingua originale	English
pagine (da-a)	267-270
Numero di pagine	4
Rivista	Clinical Nuclear Medicine
DOI	https://doi.org/10.1097/RLU.0b013e31825b222f
Stato di pubblicazione	Pubblicato - 2013

Keywords

Insulinoma Imaging PET/CT

Accesso al documento

10.1097/RLU.0b013e31825b222f

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abstract = "ABSTRACT: A 65-year-old woman with suspected insulinoma on the basis of clinical, biochemical, and conventional imaging data underwent F-dihydroxyphenylalanine (DOPA) PET/CT and Ga-DOTANOC PET/CT. F-DOPA PET/CT did not show any focal uptake in the pancreas, whereas Ga-DOTANOC PET/CT showed a focal area of intense uptake in the pancreatic tail. The patient underwent surgery and an insulinoma of about 20 mm in diameter was detected in the pancreatic tail. F-DOPA PET may fail in localizing insulin secreting tumors in adults; in these cases, the use of Ga-somatostatin analogs may lead to the correct diagnosis.",

keywords = "Insulinoma Imaging PET/CT, Insulinoma Imaging PET/CT",

author = "Guido Rindi and Salvatore Agnes and Alessandro Giordano and Vittoria Rufini and Giorgio Treglia and Frediano Inzani and Nicoletta Campanini",

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pages = "267--270",

journal = "Clinical Nuclear Medicine",

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TY - JOUR

T1 - A Case of Insulinoma Detected by 68Ga-DOTANOC PET/CT and Missed by 18F-Dihydroxyphenylalanine PET/CT

AU - Rindi, Guido

AU - Agnes, Salvatore

AU - Giordano, Alessandro

AU - Rufini, Vittoria

AU - Treglia, Giorgio

AU - Inzani, Frediano

AU - Campanini, Nicoletta

PY - 2013

Y1 - 2013

N2 - ABSTRACT: A 65-year-old woman with suspected insulinoma on the basis of clinical, biochemical, and conventional imaging data underwent F-dihydroxyphenylalanine (DOPA) PET/CT and Ga-DOTANOC PET/CT. F-DOPA PET/CT did not show any focal uptake in the pancreas, whereas Ga-DOTANOC PET/CT showed a focal area of intense uptake in the pancreatic tail. The patient underwent surgery and an insulinoma of about 20 mm in diameter was detected in the pancreatic tail. F-DOPA PET may fail in localizing insulin secreting tumors in adults; in these cases, the use of Ga-somatostatin analogs may lead to the correct diagnosis.

AB - ABSTRACT: A 65-year-old woman with suspected insulinoma on the basis of clinical, biochemical, and conventional imaging data underwent F-dihydroxyphenylalanine (DOPA) PET/CT and Ga-DOTANOC PET/CT. F-DOPA PET/CT did not show any focal uptake in the pancreas, whereas Ga-DOTANOC PET/CT showed a focal area of intense uptake in the pancreatic tail. The patient underwent surgery and an insulinoma of about 20 mm in diameter was detected in the pancreatic tail. F-DOPA PET may fail in localizing insulin secreting tumors in adults; in these cases, the use of Ga-somatostatin analogs may lead to the correct diagnosis.

KW - Insulinoma Imaging PET/CT

UR - http://hdl.handle.net/10807/42508

U2 - 10.1097/RLU.0b013e31825b222f

DO - 10.1097/RLU.0b013e31825b222f

M3 - Article

SP - 267

EP - 270

JO - Clinical Nuclear Medicine

JF - Clinical Nuclear Medicine

SN - 0363-9762

ER -

A Case of Insulinoma Detected by 68Ga-DOTANOC PET/CT and Missed by 18F-Dihydroxyphenylalanine PET/CT

Abstract

Keywords

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