TY - JOUR
T1 - A Case of Insulinoma Detected by 68Ga-DOTANOC PET/CT and Missed by 18F-Dihydroxyphenylalanine PET/CT
AU - Treglia, Giorgio
AU - Inzani, Frediano
AU - Campanini, Nicoletta
AU - Rindi, Guido
AU - Agnes, Salvatore
AU - Giordano, Alessandro
AU - Rufini, Vittoria
PY - 2013
Y1 - 2013
N2 - ABSTRACT: A 65-year-old woman with suspected insulinoma on the basis of clinical, biochemical, and conventional imaging data underwent F-dihydroxyphenylalanine (DOPA) PET/CT and Ga-DOTANOC PET/CT. F-DOPA PET/CT did not show any focal uptake in the pancreas, whereas Ga-DOTANOC PET/CT showed a focal area of intense uptake in the pancreatic tail. The patient underwent surgery and an insulinoma of about 20 mm in diameter was detected in the pancreatic tail. F-DOPA PET may fail in localizing insulin secreting tumors in adults; in these cases, the use of Ga-somatostatin analogs may lead to the correct diagnosis.
AB - ABSTRACT: A 65-year-old woman with suspected insulinoma on the basis of clinical, biochemical, and conventional imaging data underwent F-dihydroxyphenylalanine (DOPA) PET/CT and Ga-DOTANOC PET/CT. F-DOPA PET/CT did not show any focal uptake in the pancreas, whereas Ga-DOTANOC PET/CT showed a focal area of intense uptake in the pancreatic tail. The patient underwent surgery and an insulinoma of about 20 mm in diameter was detected in the pancreatic tail. F-DOPA PET may fail in localizing insulin secreting tumors in adults; in these cases, the use of Ga-somatostatin analogs may lead to the correct diagnosis.
KW - Insulinoma Imaging PET/CT
KW - Insulinoma Imaging PET/CT
UR - http://hdl.handle.net/10807/42508
U2 - 10.1097/RLU.0b013e31825b222f
DO - 10.1097/RLU.0b013e31825b222f
M3 - Article
SN - 0363-9762
SP - 267
EP - 270
JO - Clinical Nuclear Medicine
JF - Clinical Nuclear Medicine
ER -