A case of coloboma in a newborn to a woman taking mycophenolate mofetil in pregnancy after kidney transplantation.

Bianca Rocca, Mf Dei Malatesta, T Gentile, T Hadjistilianou, M Borri, S De Francesco, Francesca Pisani, A. Famulari

Risultato della ricerca: Contributo in rivistaArticolo in rivista

15 Citazioni (Scopus)

Abstract

Recently, mycophenolate mofetil (MMF) has been introduced in the immunosuppressive strategy after kidney transplantation. Recently, the existence of a MMF associated embriopathy has been hypothesized, namely, multiple craniofacial malformations. Only 1 report has described chorioretinal coloboma. We report a case of woman who used MMF throughout pregnancy after kidney transplantation. Her newborn developed coloboma of the right eye associated with an ocular cyst without any other malformation. The other drugs used by our patient are not considered teratogenic. Therefore, it seems reasonable to conclude a causal relationship between MMF and the malformation observed in this newborn.
Lingua originaleEnglish
pagine (da-a)1407-1409
Numero di pagine3
RivistaTransplantation Proceedings
Stato di pubblicazionePubblicato - 2009

Keywords

  • pregnancy
  • transplantation

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