Additional file 5: of A worldwide multicentre evaluation of the influence of deterioration or improvement of acute kidney injury on clinical outcome in critically ill patients with and without sepsis at ICU admission: results from The Intensive Care Over Nations audit

Figure S2. Hospital mortality in septic and non-septic critically ill patients during follow-up. At admission (first 72 hours in ICU), patients were categorized as No AKI and AKIN stages 1, 2 and 3, presented on x axis. Patients followed-up until day 7 to determine whether they improved to a lower AKIN stage or deteriorated to a more severe AKIN stage, presented on z axis. Hospital mortality determined for groups in which patients improved or deteriorated during follow-up. Patients with AKIN stage 3 at admission and at follow-up show highest mortality rate. Worsening of AKI is associated with higher mortality unrelated to AKI category at ICU admission. Graph also shows that patients with AKIN stage 3 at admission who improve to No AKI at follow-up still have twice as high mortality rates compared to patients with No AKI at admission and follow-up (PNG 30 kb)