Additional file 2: Figure S2. of Human mesenchymal stromal cells inhibit tumor growth in orthotopic glioblastoma xenografts

  • Simone Pacioni (Creator)
  • Quintino Giorgio D'Alessandris (Contributor)
  • Stefano Giannetti (Creator)
  • Liliana Morgante (Creator)
  • Valentina Coccè (Creator)
  • Arianna Bonomi (Creator)
  • Mariachiara Buccarelli (Contributor)
  • Luisa Pascucci (Creator)
  • Giulio Alessandri (Creator)
  • Augusto Pessina (Creator)
  • Lucia Ricci Vitiani (Creator)
  • Maria Laura Falchetti (Creator)
  • Roberto Pallini (Catholic University of the Sacred Heart) (Creator)

Dataset

Description

In vitro coculture of U87MG and GSCs with PTX-loaded or unloaded Ad-hMSCs. Coculturing tumor cells with PTX-Ad-hMSCs, but not with Ad-hMSCs, results in a strong cytotoxic effect evidenced by an increase in the number of altered spindles (white arrowhead) and multinucleated tumor cells (yellow arrows) in both U87MG (upper panel) and GSCs (lower panel) (a). Mono/multipolar spindles significantly increase both in U87MG and in GSCs at 24 h of coculture with PTX-AdMSCs (***p 
Dati resi disponibili2017
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