Utilization of small changes in serum creatinine with clinical risk factors to assess the risk of AKI in critically lll adults

Luca Montini, Massimo Antonelli, Dinna N. Cruz, Asunción Ferrer-Nadal, Pasquale Piccinni, Stuart L. Goldstein, Lakhmir S. Chawla, Elisa Alessandri, Clara Belluomo Anello, Will Bohannon, Tiziana Bove, Nicola Brienza, Mauro Carlini, Francesco Forfori, Francesco Garzotto, Silvia Gramaticopolo, Michele Iannuzzi, Paolo Pelaia, Claudio Ronco

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Disease biomarkers require appropriate clinical context to be used effectively. Combining clinical risk factors, in addition to small changes in serum creatinine, has been proposed to improve the assessment of AKI. This notion was developed in order to identify the risk of AKI early in a patient's clinical course. We set out to assess the performance of this combination approach.
Original languageEnglish
Pages (from-to)663-672
Number of pages10
JournalCLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Volume9
DOIs
Publication statusPublished - 2014

Keywords

  • Acute Kidney Injury
  • Adult
  • Age Factors
  • Aged
  • Area Under Curve
  • Biomarkers
  • Creatinine
  • Critical Illness
  • Female
  • Humans
  • Intensive Care Units
  • Italy
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Prognosis
  • Prospective Studies
  • ROC Curve
  • Risk Assessment
  • Risk Factors
  • Time Factors
  • Up-Regulation

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