Trabectedin as single agent in the salvage treatment of heavily treated ovarian cancer patients: a retrospective, multicenter study

Maria Gabriella Ferrandina, Vanda Salutari, Bruno Vincenzi, Marco Marinaccio, Emanuele Naglieri, Vera Loizzi, Silvia Carpano, Giulia Amadio, Giuseppe Tonini, Giovanni Scambia, Domenica Lorusso

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The aim of this multicenter, retrospective study was to evaluate the efficacy and the safety of single agent Trabectedin (ET-743, Yondelis) in very heavily treated, relapsed ovarian cancer (ROC) patients.
Original languageEnglish
Pages (from-to)505-510
Number of pages6
JournalGynecologic Oncology
Volume130
DOIs
Publication statusPublished - 2013

Keywords

  • Adult
  • Aged
  • Alanine Transaminase
  • Antineoplastic Agents, Alkylating
  • Aspartate Aminotransferases
  • Asthenia
  • Carcinoma
  • Dioxoles
  • Disease-Free Survival
  • Drug Resistance, Neoplasm
  • Female
  • Humans
  • Middle Aged
  • Neutropenia
  • Ovarian Neoplasms
  • Ovarian cancer
  • Platinum Compounds
  • Retrospective Studies
  • Salvage Therapy
  • Salvage treatment
  • Tetrahydroisoquinolines
  • Trabectedin

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