Therapeutic amnioinfusions and fetal fibronectin pattern in a case with preterm ruptured membranes that resealed

Sara De Carolis; Brigida Carducci; Lidia De Santis; Sergio Ferrazzani; Alessandro Caruso; Giuseppe Noia; A. Merola

Therapeutic amnioinfusions and fetal fibronectin pattern in a case with preterm ruptured membranes that resealed

Sara De Carolis, Brigida Carducci, Lidia De Santis, Sergio Ferrazzani, Alessandro Caruso, Giuseppe Noia, A. Merola

Research output: Contribution to journal › Article

Abstract

OBJECTIVE: Determination of fetal fibronectin (fFN) levels in a patient at risk of preterm delivery and having premature rupture of the membranes. PATIENT AND METHODS: The present case report concerns a pregnant woman with premature rupture of the membranes at 16 weeks of gestation who was submitted to repeated therapeutic transabdominal amnioinfusions and had a spontaneous resolution of the rupture at 32 weeks of gestation. RESULTS: A good pregnancy outcome was observed. High cervicovaginal fFN levels were observed during the period of membrane rupture with following drop of fFN levels during this period and spontaneous reseal of the membranes. CONCLUSIONS: Active expectant management, using repeated amnioinfusions, probably played a useful role in the therapeutic success of this pregnancy. Further, fFN was a reliable marker of the rupture of membranes. The possible role of fFN in the clinical management of high-risk pregnancies is confirmed

Original language	English
Pages (from-to)	66-68
Number of pages	3
Journal	Fetal Diagnosis and Therapy
Publication status	Published - 1998

Keywords

amnioinfusion

Cite this

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title = "Therapeutic amnioinfusions and fetal fibronectin pattern in a case with preterm ruptured membranes that resealed",

abstract = "OBJECTIVE: Determination of fetal fibronectin (fFN) levels in a patient at risk of preterm delivery and having premature rupture of the membranes. PATIENT AND METHODS: The present case report concerns a pregnant woman with premature rupture of the membranes at 16 weeks of gestation who was submitted to repeated therapeutic transabdominal amnioinfusions and had a spontaneous resolution of the rupture at 32 weeks of gestation. RESULTS: A good pregnancy outcome was observed. High cervicovaginal fFN levels were observed during the period of membrane rupture with following drop of fFN levels during this period and spontaneous reseal of the membranes. CONCLUSIONS: Active expectant management, using repeated amnioinfusions, probably played a useful role in the therapeutic success of this pregnancy. Further, fFN was a reliable marker of the rupture of membranes. The possible role of fFN in the clinical management of high-risk pregnancies is confirmed",

keywords = "amnioinfusion, amnioinfusion",

author = "{De Carolis}, Sara and Brigida Carducci and {De Santis}, Lidia and Sergio Ferrazzani and Alessandro Caruso and Giuseppe Noia and A. Merola",

year = "1998",

language = "English",

pages = "66--68",

journal = "Fetal Diagnosis and Therapy",

issn = "1015-3837",

publisher = "S. Karger AG",

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TY - JOUR

T1 - Therapeutic amnioinfusions and fetal fibronectin pattern in a case with preterm ruptured membranes that resealed

AU - De Carolis, Sara

AU - Carducci, Brigida

AU - De Santis, Lidia

AU - Ferrazzani, Sergio

AU - Caruso, Alessandro

AU - Noia, Giuseppe

AU - Merola, A.

PY - 1998

Y1 - 1998

N2 - OBJECTIVE: Determination of fetal fibronectin (fFN) levels in a patient at risk of preterm delivery and having premature rupture of the membranes. PATIENT AND METHODS: The present case report concerns a pregnant woman with premature rupture of the membranes at 16 weeks of gestation who was submitted to repeated therapeutic transabdominal amnioinfusions and had a spontaneous resolution of the rupture at 32 weeks of gestation. RESULTS: A good pregnancy outcome was observed. High cervicovaginal fFN levels were observed during the period of membrane rupture with following drop of fFN levels during this period and spontaneous reseal of the membranes. CONCLUSIONS: Active expectant management, using repeated amnioinfusions, probably played a useful role in the therapeutic success of this pregnancy. Further, fFN was a reliable marker of the rupture of membranes. The possible role of fFN in the clinical management of high-risk pregnancies is confirmed

AB - OBJECTIVE: Determination of fetal fibronectin (fFN) levels in a patient at risk of preterm delivery and having premature rupture of the membranes. PATIENT AND METHODS: The present case report concerns a pregnant woman with premature rupture of the membranes at 16 weeks of gestation who was submitted to repeated therapeutic transabdominal amnioinfusions and had a spontaneous resolution of the rupture at 32 weeks of gestation. RESULTS: A good pregnancy outcome was observed. High cervicovaginal fFN levels were observed during the period of membrane rupture with following drop of fFN levels during this period and spontaneous reseal of the membranes. CONCLUSIONS: Active expectant management, using repeated amnioinfusions, probably played a useful role in the therapeutic success of this pregnancy. Further, fFN was a reliable marker of the rupture of membranes. The possible role of fFN in the clinical management of high-risk pregnancies is confirmed

KW - amnioinfusion

UR - http://hdl.handle.net/10807/20647

M3 - Article

SN - 1015-3837

SP - 66

EP - 68

JO - Fetal Diagnosis and Therapy

JF - Fetal Diagnosis and Therapy

ER -

Therapeutic amnioinfusions and fetal fibronectin pattern in a case with preterm ruptured membranes that resealed

Abstract

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