TY - JOUR
T1 - The Use of Ropivacaine in Therapeutic Treatment of Oral Aphthosis
AU - Gasparini, Giulio
AU - Saponaro, Gianmarco
AU - Gasparini, Daniela
AU - Foresta, Enrico
AU - Azzuni, Camillo
AU - Adduci, Alessia
AU - Boniello, Roberto
AU - Moro, Alessandro
AU - De Angelis, Paolo
AU - Di Nardo, Francesco
AU - Damato, Giuseppe
AU - Doneddu, Piero
AU - Todaro, Mattia
AU - Garagiola, Umberto
AU - Pelo, Sando
PY - 2018
Y1 - 2018
N2 - The use of anaesthetic drugs in the treatment of oral aphthosis is one of the pharmaceutical possibilities that a doctor can use for the most painful forms. Normally, Lidocaine or Diclofenac is used to treat this disease, but they can be used for a very limited time and so they are of little practical use. In this study, the authors have used Ropivacaine whose pharmaceutical kinetics allows the analgesic effect to be active for 60 to 90 minutes. In our research, we compared 8 groups of patients who have been given 3 principal pharmaceutical products: one group was given an anaesthetic drug, one had a topical medication administered which is often used for the treatment of aphthous lesions, and the last group was given a multivitamin. These pharmaceutical products were used alone and in various possible combinations in the 8 groups. The results of this study are very interesting and show that in all the groups that used anaesthetics there was more satisfaction on the patients' part because their pain level became more manageable right after the first application of the drug and the patients could carry on with their normal lives.
AB - The use of anaesthetic drugs in the treatment of oral aphthosis is one of the pharmaceutical possibilities that a doctor can use for the most painful forms. Normally, Lidocaine or Diclofenac is used to treat this disease, but they can be used for a very limited time and so they are of little practical use. In this study, the authors have used Ropivacaine whose pharmaceutical kinetics allows the analgesic effect to be active for 60 to 90 minutes. In our research, we compared 8 groups of patients who have been given 3 principal pharmaceutical products: one group was given an anaesthetic drug, one had a topical medication administered which is often used for the treatment of aphthous lesions, and the last group was given a multivitamin. These pharmaceutical products were used alone and in various possible combinations in the 8 groups. The results of this study are very interesting and show that in all the groups that used anaesthetics there was more satisfaction on the patients' part because their pain level became more manageable right after the first application of the drug and the patients could carry on with their normal lives.
KW - Biochemistry, Genetics and Molecular Biology (all)
KW - Immunology and Microbiology (all)
KW - Biochemistry, Genetics and Molecular Biology (all)
KW - Immunology and Microbiology (all)
UR - http://hdl.handle.net/10807/123493
UR - http://www.hindawi.com/journals/biomed/
U2 - 10.1155/2018/1868254
DO - 10.1155/2018/1868254
M3 - Article
SN - 2314-6133
VL - 2018
SP - 1
EP - 8
JO - BioMed Research International
JF - BioMed Research International
ER -