The role of diet on the clinical pharmacology of oral antineoplastic agents

Antonio Ruggiero; Maria Giuseppina Cefalo; Paola Coccia; Stefano Mastrangelo; Palma Maurizi; Riccardo Riccardi

doi:10.1007/s00228-011-1102-8

The role of diet on the clinical pharmacology of oral antineoplastic agents

Antonio Ruggiero
, Maria Giuseppina Cefalo
, Paola Coccia
, Stefano Mastrangelo
, Palma Maurizi
, Riccardo Riccardi

Research output: Contribution to journal › Article

19 Citations (Scopus)

Abstract

The number of oral anticancer agents has greatly increased in recent years. It is a well-known fact that food intake can induce significant variations in the bioavailability of these drugs. The aim of this review is to describe the interactions between diet and oral anticancer drugs in terms of the possible effects of such interactions on reducing the antineoplastic activity of the drug or increasing its side effects.

Original language	English
Pages (from-to)	115-122
Number of pages	8
Journal	European Journal of Clinical Pharmacology
Volume	68
DOIs	https://doi.org/10.1007/s00228-011-1102-8
Publication status	Published - 2012

Keywords

Administration, Oral
Antineoplastic Agents
Biological Availability
Diet
Food-Drug Interactions
Humans
Neoplasms

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10.1007/s00228-011-1102-8

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title = "The role of diet on the clinical pharmacology of oral antineoplastic agents",

abstract = "The number of oral anticancer agents has greatly increased in recent years. It is a well-known fact that food intake can induce significant variations in the bioavailability of these drugs. The aim of this review is to describe the interactions between diet and oral anticancer drugs in terms of the possible effects of such interactions on reducing the antineoplastic activity of the drug or increasing its side effects.",

keywords = "Administration, Oral, Antineoplastic Agents, Biological Availability, Diet, Food-Drug Interactions, Humans, Neoplasms, Administration, Oral, Antineoplastic Agents, Biological Availability, Diet, Food-Drug Interactions, Humans, Neoplasms",

author = "Antonio Ruggiero and Cefalo, \{Maria Giuseppina\} and Paola Coccia and Stefano Mastrangelo and Palma Maurizi and Riccardo Riccardi",

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doi = "10.1007/s00228-011-1102-8",

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pages = "115--122",

journal = "European Journal of Clinical Pharmacology",

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T1 - The role of diet on the clinical pharmacology of oral antineoplastic agents

AU - Ruggiero, Antonio

AU - Cefalo, Maria Giuseppina

AU - Coccia, Paola

AU - Mastrangelo, Stefano

AU - Maurizi, Palma

AU - Riccardi, Riccardo

PY - 2012

Y1 - 2012

N2 - The number of oral anticancer agents has greatly increased in recent years. It is a well-known fact that food intake can induce significant variations in the bioavailability of these drugs. The aim of this review is to describe the interactions between diet and oral anticancer drugs in terms of the possible effects of such interactions on reducing the antineoplastic activity of the drug or increasing its side effects.

AB - The number of oral anticancer agents has greatly increased in recent years. It is a well-known fact that food intake can induce significant variations in the bioavailability of these drugs. The aim of this review is to describe the interactions between diet and oral anticancer drugs in terms of the possible effects of such interactions on reducing the antineoplastic activity of the drug or increasing its side effects.

KW - Administration, Oral

KW - Antineoplastic Agents

KW - Biological Availability

KW - Diet

KW - Food-Drug Interactions

KW - Humans

KW - Neoplasms

KW - Administration, Oral

KW - Antineoplastic Agents

KW - Biological Availability

KW - Diet

KW - Food-Drug Interactions

KW - Humans

KW - Neoplasms

UR - http://hdl.handle.net/10807/30707

U2 - 10.1007/s00228-011-1102-8

DO - 10.1007/s00228-011-1102-8

M3 - Article

SN - 0031-6970

VL - 68

SP - 115

EP - 122

JO - European Journal of Clinical Pharmacology

JF - European Journal of Clinical Pharmacology

ER -

The role of diet on the clinical pharmacology of oral antineoplastic agents

Abstract

Keywords

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