The Role of CD56 in Thyroid Fine Needle Aspiration Cytology: A Pilot Study Performed on Liquid Based Cytology

Maurizio Martini, Celestino Pio Lombardi, Alfredo Pontecorvi, Luigi Maria Larocca, Esther Rossi, Tommaso Bizzarro, Emanuela Traini, Guido Fadda

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Fine needle aspiration Cytology (FNAC) fulfills a reliable role in the evaluation of thyroid lesions. Although the majority of nodules are quite easily diagnosed as benign or malignant, 30% of them represent an indeterminate category whereby the application of ancillary techniques (i.e. immunocytochemistry-ICC and molecular testing) has been encouraged. The search for a specific immunomarker of malignancy sheds light on a huge number of ICC stains although none of them attempt to yield 100% conclusive results. Our aim was to define in a pilot study on thyroid FNAC whether CD56 might be a valid marker also in comparison with HBME-1 and Galectin-3.
Original languageEnglish
Pages (from-to)e0132939-e0132939
JournalPLoS One
Volume10
DOIs
Publication statusPublished - 2015

Keywords

  • Fine Needle Aspiration

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