The Impact of the 2022 WHO Classification of Thyroid Neoplasms on Everyday Practice of Cytopathology

Esther Rossi, Zubair Baloch

Research output: Contribution to journalArticle

Abstract

This review outlines how the alterations in the 5th edition of the WHO Classification of Endocrine and Neuroendocrine Tumors of the thyroid gland are likely to impact thyroid cytopathology. It is important to note that WHO subclassifies thyroid tumors into several new categories based on increased comprehension of the cell of origin, pathologic features (including cytopathology), molecular classification, and biological behavior. The 3rd edition of the Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) will debut in the near future and will include changes in diagnostic category designations. The changes in the 5th edition of the WHO will in some instances subtly, and in other instances significantly, impact the cytological diagnoses. Moreover, these changes will also affect other thyroid FNA classification schemes used internationally for classifying thyroid FNA specimens.
Original languageEnglish
Pages (from-to)23-33
Number of pages11
JournalEndocrine Pathology
Volume34
DOIs
Publication statusPublished - 2023

Keywords

  • Molecular testing
  • Personalized medicine
  • WHO
  • Thyroid cytology
  • Thyroid diagnostic categories
  • Thyroid cancers

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