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The hbhA gene of Mycobacterium tuberculosis is specifically upregulated in the lungs but not in the spleens of aerogenically infected mice

Research output: Contribution to journalArticlepeer-review

Abstract

We report that hbhA is differentially regulated during Mycobacterium tuberculosis infection. Upregulation was observed in epithelial cell infection but not in macrophage infection and in the lungs but not in the spleens of infected mice, and it was greater during the early steps of infection, when bacilli disseminate from the site of primary infection.
Original languageEnglish
Pages (from-to)3006-3011
Number of pages6
JournalInfection and Immunity
Volume74
DOIs
Publication statusPublished - 2006

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Animals
  • Bacterial Proteins
  • Cytoskeletal Proteins
  • Female
  • Gene Expression Regulation, Bacterial
  • Lung
  • Membrane Proteins
  • Mice
  • Mice, Inbred C57BL
  • Organ Specificity
  • Recombinant Proteins
  • Spleen
  • Up-Regulation

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