The fate of a macroporous hydroxyapatite cranioplasty four years after implantation: Macroscopical and microscopical findings in a case of recurrent atypical meningioma

Paolo Frassanito; Pasquale De Bonis; Pier Paolo Mattogno; Annunziato Mangiola; Mariangela Novello; Domenico Brinchi; Angelo Pompucci; Carmelo Anile

doi:10.1016/j.clineuro.2012.11.032

The fate of a macroporous hydroxyapatite cranioplasty four years after implantation: Macroscopical and microscopical findings in a case of recurrent atypical meningioma

Paolo Frassanito, Pasquale De Bonis, Pier Paolo Mattogno, Annunziato Mangiola, Mariangela Novello, Domenico Brinchi, Angelo Pompucci, Carmelo Anile

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Abstract

Reconstruction of calvarial bone defects can be achieved using autologous bone or a wide range of prosthetic materials [1]. Macroporous hydroxyapatite (MH) has histologically proven its potential osteointegration in animal models [2], [3] and [4]. Recent radiological and clinical data in human subjects are in favour of good osteointegration of MH cranioplasty [5] and [6]. However, the MH implant has weak mechanic stability and is prone to fractures [7]. Furthermore, it is not known how fast and to which extent the implant is ossified in vivo. We report a case with limited ossification of a MH prosthesis four years after implantation

Original language	English
Pages (from-to)	N/A-N/A
Journal	Clinical Neurology and Neurosurgery
DOIs	https://doi.org/10.1016/j.clineuro.2012.11.032
Publication status	Published - 2012

Keywords

cranioplasty

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10.1016/j.clineuro.2012.11.032

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Frassanito, P., De Bonis, P., Mattogno, P. P., Mangiola, A., Novello, M., Brinchi, D., Pompucci, A., & Anile, C. (2012). The fate of a macroporous hydroxyapatite cranioplasty four years after implantation: Macroscopical and microscopical findings in a case of recurrent atypical meningioma. Clinical Neurology and Neurosurgery, N/A-N/A. https://doi.org/10.1016/j.clineuro.2012.11.032

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title = "The fate of a macroporous hydroxyapatite cranioplasty four years after implantation: Macroscopical and microscopical findings in a case of recurrent atypical meningioma",

abstract = "Reconstruction of calvarial bone defects can be achieved using autologous bone or a wide range of prosthetic materials [1]. Macroporous hydroxyapatite (MH) has histologically proven its potential osteointegration in animal models [2], [3] and [4]. Recent radiological and clinical data in human subjects are in favour of good osteointegration of MH cranioplasty [5] and [6]. However, the MH implant has weak mechanic stability and is prone to fractures [7]. Furthermore, it is not known how fast and to which extent the implant is ossified in vivo. We report a case with limited ossification of a MH prosthesis four years after implantation",

keywords = "cranioplasty, cranioplasty",

author = "Paolo Frassanito and {De Bonis}, Pasquale and Mattogno, {Pier Paolo} and Annunziato Mangiola and Mariangela Novello and Domenico Brinchi and Angelo Pompucci and Carmelo Anile",

year = "2012",

doi = "10.1016/j.clineuro.2012.11.032",

language = "English",

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journal = "Clinical Neurology and Neurosurgery",

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publisher = "Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598",

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Frassanito, P, De Bonis, P, Mattogno, PP, Mangiola, A, Novello, M, Brinchi, D, Pompucci, A & Anile, C 2012, 'The fate of a macroporous hydroxyapatite cranioplasty four years after implantation: Macroscopical and microscopical findings in a case of recurrent atypical meningioma', Clinical Neurology and Neurosurgery, pp. N/A-N/A. https://doi.org/10.1016/j.clineuro.2012.11.032

TY - JOUR

T1 - The fate of a macroporous hydroxyapatite cranioplasty four years after implantation: Macroscopical and microscopical findings in a case of recurrent atypical meningioma

AU - Frassanito, Paolo

AU - De Bonis, Pasquale

AU - Mattogno, Pier Paolo

AU - Mangiola, Annunziato

AU - Novello, Mariangela

AU - Brinchi, Domenico

AU - Pompucci, Angelo

AU - Anile, Carmelo

PY - 2012

Y1 - 2012

N2 - Reconstruction of calvarial bone defects can be achieved using autologous bone or a wide range of prosthetic materials [1]. Macroporous hydroxyapatite (MH) has histologically proven its potential osteointegration in animal models [2], [3] and [4]. Recent radiological and clinical data in human subjects are in favour of good osteointegration of MH cranioplasty [5] and [6]. However, the MH implant has weak mechanic stability and is prone to fractures [7]. Furthermore, it is not known how fast and to which extent the implant is ossified in vivo. We report a case with limited ossification of a MH prosthesis four years after implantation

AB - Reconstruction of calvarial bone defects can be achieved using autologous bone or a wide range of prosthetic materials [1]. Macroporous hydroxyapatite (MH) has histologically proven its potential osteointegration in animal models [2], [3] and [4]. Recent radiological and clinical data in human subjects are in favour of good osteointegration of MH cranioplasty [5] and [6]. However, the MH implant has weak mechanic stability and is prone to fractures [7]. Furthermore, it is not known how fast and to which extent the implant is ossified in vivo. We report a case with limited ossification of a MH prosthesis four years after implantation

KW - cranioplasty

UR - http://hdl.handle.net/10807/41596

U2 - 10.1016/j.clineuro.2012.11.032

DO - 10.1016/j.clineuro.2012.11.032

M3 - Article

SN - 0303-8467

SP - N/A-N/A

JO - Clinical Neurology and Neurosurgery

JF - Clinical Neurology and Neurosurgery

ER -

The fate of a macroporous hydroxyapatite cranioplasty four years after implantation: Macroscopical and microscopical findings in a case of recurrent atypical meningioma

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Keywords

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