Terutroban versus aspirin in patients with cerebral ischaemic events (PERFORM): a randomised, double-blind, parallel-group trial

Paolo Maria Rossini, M Bousser, P Amarenco, A Chamorro, M Fisher, I Ford, Km Fox, Mg Hennerici, Hp Mattle, Pm Rothwell, A De Cordoüe, M Fratacci

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168 Citations (Scopus)

Abstract

Patients with ischaemic stroke or transient ischaemic attack (TIA) are at high risk of recurrent stroke or other cardiovascular events. We compared the selective thromboxane-prostaglandin receptor antagonist terutroban with aspirin in the prevention of cerebral and cardiovascular ischaemic events in patients with a recent non-cardioembolic cerebral ischaemic event.
Original languageEnglish
Pages (from-to)2013-2022
Number of pages10
JournalLANCET
Volume377
DOIs
Publication statusPublished - 2011

Keywords

  • Aged
  • Aspirin
  • Double-Blind Method
  • Female
  • Humans
  • Ischemic Attack, Transient
  • Male
  • Middle Aged
  • Naphthalenes
  • Platelet Aggregation Inhibitors
  • Propionic Acids
  • Receptors, Thromboxane
  • Secondary Prevention
  • Stroke
  • Treatment Outcome

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