Switch to raltegravir-based regimens and HIV DNA decrease in patients with suppressed HIV RNA

Nicoletta Ciccarelli, Simona Di Giambenedetto, Claudia Bianco, Barbara Rossetti, Annalisa Mondi, Andrea De Luca, G Meini, S Lamonica, S Belmonti, L Fanti, M Zazzi

Research output: Contribution to journalConference articlepeer-review

Abstract

Raltegravir intensification is associated with an increase in 2-LTR episomal HIV DNA= circles, indicating a persistent low-level replication, in some individuals in ART with suppressed HIV RNA. We aimed at monitoring residual plasma HIV RNA and cellular HIV DNA in virologically suppressed patients switching to a raltegravir-based regimen.
Original languageEnglish
Pages (from-to)19791-19791
Number of pages1
JournalJournal of the International AIDS Society
Volume17
DOIs
Publication statusPublished - 2014
EventHIV Drug Therapy Glasgow Congress 2014 - Glasgow
Duration: 23 Oct 201426 Oct 2014

Keywords

  • DNA
  • HIV
  • therapy

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