Switch to raltegravir-based regimens and HIV DNA decrease in patients with suppressed HIV RNA

Claudia Bianco; G Meini; Barbara Rossetti; S Lamonica; Annalisa Mondi; S Belmonti; L Fanti; Nicoletta Ciccarelli; Simona Di Giambenedetto; M Zazzi; Andrea De Luca

doi:10.7448/IAS.17.4.19791

Switch to raltegravir-based regimens and HIV DNA decrease in patients with suppressed HIV RNA

Claudia Bianco, G Meini, Barbara Rossetti, S Lamonica, Annalisa Mondi, S Belmonti, L Fanti, Nicoletta Ciccarelli, Simona Di Giambenedetto, M Zazzi, Andrea De Luca

Research output: Contribution to journal › Conference article › peer-review

Abstract

Raltegravir intensification is associated with an increase in 2-LTR episomal HIV DNA= circles, indicating a persistent low-level replication, in some individuals in ART with suppressed HIV RNA. We aimed at monitoring residual plasma HIV RNA and cellular HIV DNA in virologically suppressed patients switching to a raltegravir-based regimen.

Original language	English
Pages (from-to)	19791-19791
Number of pages	1
Journal	Journal of the International AIDS Society
Volume	17
DOIs	https://doi.org/10.7448/IAS.17.4.19791
Publication status	Published - 2014
Event	HIV Drug Therapy Glasgow Congress 2014 - Glasgow Duration: 23 Oct 2014 → 26 Oct 2014

Keywords

DNA
HIV
therapy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.7448/IAS.17.4.19791

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@article{f20ce332afe04d7da08ec37fe71185f9,

title = "Switch to raltegravir-based regimens and HIV DNA decrease in patients with suppressed HIV RNA",

abstract = "Raltegravir intensification is associated with an increase in 2-LTR episomal HIV DNA= circles, indicating a persistent low-level replication, in some individuals in ART with suppressed HIV RNA. We aimed at monitoring residual plasma HIV RNA and cellular HIV DNA in virologically suppressed patients switching to a raltegravir-based regimen.",

keywords = "DNA, HIV, therapy, DNA, HIV, therapy",

author = "Claudia Bianco and G Meini and Barbara Rossetti and S Lamonica and Annalisa Mondi and S Belmonti and L Fanti and Nicoletta Ciccarelli and {Di Giambenedetto}, Simona and M Zazzi and {De Luca}, Andrea",

year = "2014",

doi = "10.7448/IAS.17.4.19791",

language = "English",

volume = "17",

pages = "19791--19791",

journal = "Journal of the International AIDS Society",

issn = "1758-2652",

publisher = "John Wiley & Sons Inc.",

note = "HIV Drug Therapy Glasgow Congress 2014 ; Conference date: 23-10-2014 Through 26-10-2014",

}

TY - JOUR

T1 - Switch to raltegravir-based regimens and HIV DNA decrease in patients with suppressed HIV RNA

AU - Bianco, Claudia

AU - Meini, G

AU - Rossetti, Barbara

AU - Lamonica, S

AU - Mondi, Annalisa

AU - Belmonti, S

AU - Fanti, L

AU - Ciccarelli, Nicoletta

AU - Di Giambenedetto, Simona

AU - Zazzi, M

AU - De Luca, Andrea

PY - 2014

Y1 - 2014

N2 - Raltegravir intensification is associated with an increase in 2-LTR episomal HIV DNA= circles, indicating a persistent low-level replication, in some individuals in ART with suppressed HIV RNA. We aimed at monitoring residual plasma HIV RNA and cellular HIV DNA in virologically suppressed patients switching to a raltegravir-based regimen.

AB - Raltegravir intensification is associated with an increase in 2-LTR episomal HIV DNA= circles, indicating a persistent low-level replication, in some individuals in ART with suppressed HIV RNA. We aimed at monitoring residual plasma HIV RNA and cellular HIV DNA in virologically suppressed patients switching to a raltegravir-based regimen.

KW - DNA

KW - HIV

KW - therapy

KW - DNA

KW - HIV

KW - therapy

UR - http://hdl.handle.net/10807/61290

U2 - 10.7448/IAS.17.4.19791

DO - 10.7448/IAS.17.4.19791

M3 - Conference article

SN - 1758-2652

VL - 17

SP - 19791

EP - 19791

JO - Journal of the International AIDS Society

JF - Journal of the International AIDS Society

T2 - HIV Drug Therapy Glasgow Congress 2014

Y2 - 23 October 2014 through 26 October 2014

ER -

Switch to raltegravir-based regimens and HIV DNA decrease in patients with suppressed HIV RNA

Abstract

Keywords

UN SDGs

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