Swept-source OCT reduces the risk of axial length measurement errors in eyes with cataract and epiretinal membranes

Francesco Faraldi, Carlo Alessandro Lavia, Marco Nassisi, Raphael A. Kilian, Daniela Bacherini, Stanislao Rizzo

Research output: Contribution to journalArticle


AimsTo compare the biometric data from partial coherence interferometry (PCI) and swept-source OCT (SS-OCT) in patients with age-related cataract and epiretinal membrane (ERM): ERM, ERM with foveoschisis and macular pseudohole.Methods49 eyes of 49 subjects including 36 ERM, 9 ERM foveoschisis and 4 macular pseudohole were analysed to evaluate the axial length (AL) measurements and the presence of AL measurement errors, defined basing on the shape of the biometric output graphs and on the concordance of AL values between instruments. Eyes with ERM were divided in four stages according to OCT features (i.e. presence/absence of the foveal pit, presence of ectopic inner foveal layers, disrupted retinal layers).ResultsThe devices provided similar mean AL measurements in all subgroups, with differences <0.1 mm in 41/49 cases (83.6%). AL measurement errors were observed in ERM stages 3 and 4, characterized by ectopic inner foveal layers, and were significantly more frequent with the PCI (8/17, 47%) as compared with the SS-OCT device (2/17, 12%), p = 0.02. The refractive prediction error in cases with AL measurement errors was significantly greater using the PCI compared to the SS-OCT device (p<0.05).ConclusionBoth devices provide reliable biometric data in the majority of patients and can be used in the preoperative assessment of patients with age-related cataract and ERM. In eyes with ectopic inner foveal layers, attention should be paid as AL measurement and refractive prediction errors may occur, more frequently with the PCI device.
Original languageEnglish
Pages (from-to)1-11
Number of pages11
JournalPLoS One
Publication statusPublished - 2021


  • Epiretinal Membrane
  • Swept-source OCT


Dive into the research topics of 'Swept-source OCT reduces the risk of axial length measurement errors in eyes with cataract and epiretinal membranes'. Together they form a unique fingerprint.

Cite this