Surgical Planning after Neoadjuvant Treatment in Breast Cancer: A Multimodality Imaging-Based Approach Focused on MRI

M. Conti; F. Morciano; E. Bufi; A. D'Angelo; C. Panico; Paola V. Di; E. Gori; G. Russo; G. Cimino; S. Palma; Paolo Belli; Riccardo Manfredi

doi:10.3390/cancers15051439

Abstract

Neoadjuvant chemotherapy (NACT) today represents a cornerstone in the treatment of locally advanced breast cancer and highly chemo-sensitive tumors at early stages, increasing the possibilities of performing more conservative treatments and improving long term outcomes. Imaging has a fundamental role in the staging and prediction of the response to NACT, thus aiding surgical planning and avoiding overtreatment. In this review, we first examine and compare the role of conventional and advanced imaging techniques in preoperative T Staging after NACT and in the evaluation of lymph node involvement. In the second part, we analyze the different surgical approaches, discussing the role of axillary surgery, as well as the possibility of non-operative management after-NACT, which has been the subject of recent trials. Finally, we focus on emerging techniques that will change the diagnostic assessment of breast cancer in the near future.

Original language	English
Pages (from-to)	N/A-N/A
Journal	Cancers
Volume	15
Issue number	5
DOIs	https://doi.org/10.3390/cancers15051439
Publication status	Published - 2023

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

Keywords

axillary lymphadenectomy (AL)
breast-conservative surgery (BCS)
clipped lymph node (CL)
conservative mastectomy with reconstruction (CMR)
locally advanced breast cancer (LABC)
magnetic resonance imaging (MRI)
neoadjuvant chemotherapy (NACT)
oncoplastic surgery (OPS)
selective axillary dissection (SAD)
sentinel lymph node biopsy technique (SLNB)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.3390/cancers15051439

Cite this

@article{f03fc1e3cbea4981bfa67494df3af343,

title = "Surgical Planning after Neoadjuvant Treatment in Breast Cancer: A Multimodality Imaging-Based Approach Focused on MRI",

abstract = "Neoadjuvant chemotherapy (NACT) today represents a cornerstone in the treatment of locally advanced breast cancer and highly chemo-sensitive tumors at early stages, increasing the possibilities of performing more conservative treatments and improving long term outcomes. Imaging has a fundamental role in the staging and prediction of the response to NACT, thus aiding surgical planning and avoiding overtreatment. In this review, we first examine and compare the role of conventional and advanced imaging techniques in preoperative T Staging after NACT and in the evaluation of lymph node involvement. In the second part, we analyze the different surgical approaches, discussing the role of axillary surgery, as well as the possibility of non-operative management after-NACT, which has been the subject of recent trials. Finally, we focus on emerging techniques that will change the diagnostic assessment of breast cancer in the near future.",

keywords = "axillary lymphadenectomy (AL), breast-conservative surgery (BCS), clipped lymph node (CL), conservative mastectomy with reconstruction (CMR), locally advanced breast cancer (LABC), magnetic resonance imaging (MRI), neoadjuvant chemotherapy (NACT), oncoplastic surgery (OPS), selective axillary dissection (SAD), sentinel lymph node biopsy technique (SLNB), axillary lymphadenectomy (AL), breast-conservative surgery (BCS), clipped lymph node (CL), conservative mastectomy with reconstruction (CMR), locally advanced breast cancer (LABC), magnetic resonance imaging (MRI), neoadjuvant chemotherapy (NACT), oncoplastic surgery (OPS), selective axillary dissection (SAD), sentinel lymph node biopsy technique (SLNB)",

author = "M. Conti and F. Morciano and E. Bufi and A. D'Angelo and C. Panico and Di, \{Paola V.\} and E. Gori and G. Russo and G. Cimino and S. Palma and Paolo Belli and Riccardo Manfredi",

year = "2023",

doi = "10.3390/cancers15051439",

language = "English",

volume = "15",

pages = "N/A--N/A",

journal = "Cancers",

issn = "2072-6694",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "5",

}

TY - JOUR

T1 - Surgical Planning after Neoadjuvant Treatment in Breast Cancer: A Multimodality Imaging-Based Approach Focused on MRI

AU - Conti, M.

AU - Morciano, F.

AU - Bufi, E.

AU - D'Angelo, A.

AU - Panico, C.

AU - Di, Paola V.

AU - Gori, E.

AU - Russo, G.

AU - Cimino, G.

AU - Palma, S.

AU - Belli, Paolo

AU - Manfredi, Riccardo

PY - 2023

Y1 - 2023

N2 - Neoadjuvant chemotherapy (NACT) today represents a cornerstone in the treatment of locally advanced breast cancer and highly chemo-sensitive tumors at early stages, increasing the possibilities of performing more conservative treatments and improving long term outcomes. Imaging has a fundamental role in the staging and prediction of the response to NACT, thus aiding surgical planning and avoiding overtreatment. In this review, we first examine and compare the role of conventional and advanced imaging techniques in preoperative T Staging after NACT and in the evaluation of lymph node involvement. In the second part, we analyze the different surgical approaches, discussing the role of axillary surgery, as well as the possibility of non-operative management after-NACT, which has been the subject of recent trials. Finally, we focus on emerging techniques that will change the diagnostic assessment of breast cancer in the near future.

AB - Neoadjuvant chemotherapy (NACT) today represents a cornerstone in the treatment of locally advanced breast cancer and highly chemo-sensitive tumors at early stages, increasing the possibilities of performing more conservative treatments and improving long term outcomes. Imaging has a fundamental role in the staging and prediction of the response to NACT, thus aiding surgical planning and avoiding overtreatment. In this review, we first examine and compare the role of conventional and advanced imaging techniques in preoperative T Staging after NACT and in the evaluation of lymph node involvement. In the second part, we analyze the different surgical approaches, discussing the role of axillary surgery, as well as the possibility of non-operative management after-NACT, which has been the subject of recent trials. Finally, we focus on emerging techniques that will change the diagnostic assessment of breast cancer in the near future.

KW - axillary lymphadenectomy (AL)

KW - breast-conservative surgery (BCS)

KW - clipped lymph node (CL)

KW - conservative mastectomy with reconstruction (CMR)

KW - locally advanced breast cancer (LABC)

KW - magnetic resonance imaging (MRI)

KW - neoadjuvant chemotherapy (NACT)

KW - oncoplastic surgery (OPS)

KW - selective axillary dissection (SAD)

KW - sentinel lymph node biopsy technique (SLNB)

KW - axillary lymphadenectomy (AL)

KW - breast-conservative surgery (BCS)

KW - clipped lymph node (CL)

KW - conservative mastectomy with reconstruction (CMR)

KW - locally advanced breast cancer (LABC)

KW - magnetic resonance imaging (MRI)

KW - neoadjuvant chemotherapy (NACT)

KW - oncoplastic surgery (OPS)

KW - selective axillary dissection (SAD)

KW - sentinel lymph node biopsy technique (SLNB)

UR - https://publicatt.unicatt.it/handle/10807/298498

UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85149813253&origin=inward

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85149813253&origin=inward

U2 - 10.3390/cancers15051439

DO - 10.3390/cancers15051439

M3 - Meeting Abstract

SN - 2072-6694

VL - 15

SP - N/A-N/A

JO - Cancers

JF - Cancers

IS - 5

ER -