TY - JOUR
T1 - Surgical Planning after Neoadjuvant Treatment in Breast Cancer: A Multimodality Imaging-Based Approach Focused on MRI
AU - Conti, Marco
AU - Morciano, Francesca
AU - Bufi, Enida
AU - D'Angelo, Anna
AU - Panico, Camilla
AU - Di Paola, Valerio
AU - Gori, Elisabetta
AU - Russo, Gianluca
AU - Cimino, Giovanni
AU - Palma, Simone
AU - Belli, Paolo
AU - Manfredi, Riccardo
PY - 2023
Y1 - 2023
N2 - Neoadjuvant chemotherapy (NACT) today represents a cornerstone in the treatment of locally advanced breast cancer and highly chemo-sensitive tumors at early stages, increasing the possibilities of performing more conservative treatments and improving long term outcomes. Imaging has a fundamental role in the staging and prediction of the response to NACT, thus aiding surgical planning and avoiding overtreatment. In this review, we first examine and compare the role of conventional and advanced imaging techniques in preoperative T Staging after NACT and in the evaluation of lymph node involvement. In the second part, we analyze the different surgical approaches, discussing the role of axillary surgery, as well as the possibility of non-operative management after-NACT, which has been the subject of recent trials. Finally, we focus on emerging techniques that will change the diagnostic assessment of breast cancer in the near future.
AB - Neoadjuvant chemotherapy (NACT) today represents a cornerstone in the treatment of locally advanced breast cancer and highly chemo-sensitive tumors at early stages, increasing the possibilities of performing more conservative treatments and improving long term outcomes. Imaging has a fundamental role in the staging and prediction of the response to NACT, thus aiding surgical planning and avoiding overtreatment. In this review, we first examine and compare the role of conventional and advanced imaging techniques in preoperative T Staging after NACT and in the evaluation of lymph node involvement. In the second part, we analyze the different surgical approaches, discussing the role of axillary surgery, as well as the possibility of non-operative management after-NACT, which has been the subject of recent trials. Finally, we focus on emerging techniques that will change the diagnostic assessment of breast cancer in the near future.
KW - axillary lymphadenectomy (AL)
KW - breast-conservative surgery (BCS)
KW - clipped lymph node (CL)
KW - conservative mastectomy with reconstruction (CMR)
KW - sentinel lymph node biopsy technique (SLNB)
KW - magnetic resonance imaging (MRI)
KW - neoadjuvant chemotherapy (NACT)
KW - oncoplastic surgery (OPS)
KW - selective axillary dissection (SAD)
KW - locally advanced breast cancer (LABC)
KW - axillary lymphadenectomy (AL)
KW - breast-conservative surgery (BCS)
KW - clipped lymph node (CL)
KW - conservative mastectomy with reconstruction (CMR)
KW - sentinel lymph node biopsy technique (SLNB)
KW - magnetic resonance imaging (MRI)
KW - neoadjuvant chemotherapy (NACT)
KW - oncoplastic surgery (OPS)
KW - selective axillary dissection (SAD)
KW - locally advanced breast cancer (LABC)
UR - http://hdl.handle.net/10807/298498
U2 - 10.3390/cancers15051439
DO - 10.3390/cancers15051439
M3 - Meeting Abstract
SN - 2072-6694
VL - 15
SP - N/A-N/A
JO - Cancers
JF - Cancers
ER -
