TY - JOUR
T1 - Surgical and Clinical Outcomes of Microvascular Decompression: A Comparative Study between Young and Elderly Patients
AU - Menna, Grazia
AU - Rapisarda, Alessandro
AU - Izzo, Alessandro
AU - D'Ercole, Manuela
AU - D'Alessandris, Quintino Giorgio
AU - Olivi, Alessandro
AU - Montano, Nicola
PY - 2022
Y1 - 2022
N2 - Microvascular decompression (MVD) is the only etiological technique for the treatment of trigeminal neuralgia (TN). Whilst there is a consensus MVD is likely effective regardless of age, the elderly population is thought to be more prone to have a higher rate of surgical complication, morbidity, and mortality. The main objective of our single-center, retrospective study was to analyze the surgical and clinical outcomes of MVD in TN elderly patients. From a surgical series of patients with TN who had undergone MVD from April 2018 to April 2022, 76 patients who matched the inclusion criteria were divided into two groups: twenty-five (32.9%) patients were older than 65 years and included in the elderly group, while the remaining fifty-one (61.1%) patients were below 65 years included in the non-elderly one. There were no differences between the groups in terms of acute pain relief (APR), Barrow Neurological Index (BNI) at follow-up, complications, and recurrence rate. In multivariate analysis (Cox proportional hazards regression analysis) the presence of an offending artery with nerve root distortion/indentation emerged as the only independent prognostic factor for pain-free survival (p = 0.0001). Our data endorse MVD as a safe and effective surgical procedure also for elderly patients with TN.
AB - Microvascular decompression (MVD) is the only etiological technique for the treatment of trigeminal neuralgia (TN). Whilst there is a consensus MVD is likely effective regardless of age, the elderly population is thought to be more prone to have a higher rate of surgical complication, morbidity, and mortality. The main objective of our single-center, retrospective study was to analyze the surgical and clinical outcomes of MVD in TN elderly patients. From a surgical series of patients with TN who had undergone MVD from April 2018 to April 2022, 76 patients who matched the inclusion criteria were divided into two groups: twenty-five (32.9%) patients were older than 65 years and included in the elderly group, while the remaining fifty-one (61.1%) patients were below 65 years included in the non-elderly one. There were no differences between the groups in terms of acute pain relief (APR), Barrow Neurological Index (BNI) at follow-up, complications, and recurrence rate. In multivariate analysis (Cox proportional hazards regression analysis) the presence of an offending artery with nerve root distortion/indentation emerged as the only independent prognostic factor for pain-free survival (p = 0.0001). Our data endorse MVD as a safe and effective surgical procedure also for elderly patients with TN.
KW - elderly
KW - microvascular decompression
KW - surgery
KW - trigeminal neuralgia
KW - elderly
KW - microvascular decompression
KW - surgery
KW - trigeminal neuralgia
UR - http://hdl.handle.net/10807/227183
U2 - 10.3390/brainsci12091216
DO - 10.3390/brainsci12091216
M3 - Article
SN - 2076-3425
VL - 12
SP - 1216-N/A
JO - Brain Sciences
JF - Brain Sciences
ER -