Abstract
Mutations of the nucleophosmin (NPM1) gene represent the most common genetic lesion in adult acute myeloid leukemia (AML), occurring in about one-third of cases and 60% of AML with normal cytogenetics.1 Due to its unique molecular, pathological and clinical features,2, 3 NPM1-mutated AML is now recognized as a distinct entity in the 2022 International Consensus4 and World Health Organization (WHO) 5th edition5 classifications of myeloid neoplasms.
| Original language | English |
|---|---|
| Pages (from-to) | 139-143 |
| Number of pages | 5 |
| Journal | American Journal of Hematology |
| Issue number | 1 |
| Publication status | Published - 2024 |
Keywords
- American Journal of Hematology American Journal of Hematology IMAGES IN HEMATOLOGY Full Access Starry sky pattern predicts RAS pathway activation in NPM1
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