Spinal muscular atrophy associated with progressive myoclonic epilepsy: A rare condition caused by mutations in ASAH1

Guido Rubboli, Pierangelo Veggiotti, Antonella Pini, Angela Berardinelli, Gaetano Cantalupo, Enrico Bertini, Francesco Danilo Tiziano, Adele D'Amico, Elena Piazza, Emanuela Abiusi, Stefania Fiori, Elena Pasini, Francesca Darra, Giuseppe Gobbi, Roberto Michelucci

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

To present the clinical features and the results of laboratory investigations in three patients with spinal muscular atrophy associated with progressive myoclonic epilepsy (SMA-PME), a rare condition caused by mutations in the N-acylsphingosine amidohydrosilase 1 (ASAH1) gene.
Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalEpilepsia
DOIs
Publication statusPublished - 2015

Keywords

  • ASAH1 mutations
  • Myoclonus
  • Polygraphy
  • Progressive myoclonus epilepsy
  • Spinal muscular atrophy

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