Single tablet regimens are associated with reduced Efavirenz withdrawal in antiretroviral therapy naïve or switching for simplification HIV-infected patients

Massimiliano Fabbiani; M Zaccarelli; Pierfrancesco Grima; M Prosperi; Iuri Fanti; Manuela Colafigli; Alessandro D'Avino; Annalisa Mondi; Alberto Borghetti; Massimo Fantoni; Roberto Cauda; Simona Di Giambenedetto

doi:10.1186/1471-2334-14-26

Single tablet regimens are associated with reduced Efavirenz withdrawal in antiretroviral therapy naïve or switching for simplification HIV-infected patients

Massimiliano Fabbiani
, M Zaccarelli^*
, Pierfrancesco Grima
, M Prosperi
, Iuri Fanti
, Manuela Colafigli
, Alessandro D'Avino
, Annalisa Mondi
, Alberto Borghetti
, Massimo Fantoni
, Roberto Cauda
, Simona Di Giambenedetto

^*Corresponding author

S. Caterina Novella Hospital

Research output: Contribution to journal › Article

13 Citations (Scopus)

Abstract

Efavirenz (EFV) administration is still controversial for its high rates of interruption mainly related to central nervous system side effects (CNS-SE). Aim of the study was to define if single tablet regimen (STR) as compared to bis-in-die (BID) or once-daily (OD) with ≥2 pills-a-day EFV formulations reduced the risk of interruption.

Original language	English
Pages (from-to)	26-26
Number of pages	1
Journal	BMC Public Health
Volume	14
Issue number	1
DOIs	https://doi.org/10.1186/1471-2334-14-26
Publication status	Published - 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Infectious Diseases

Keywords

Efavirenz
antiretroviral
nervous system
therapy

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10.1186/1471-2334-14-26

Cite this

Fabbiani, M., Zaccarelli, M., Grima, P., Prosperi, M., Fanti, I., Colafigli, M., D'Avino, A., Mondi, A., Borghetti, A., Fantoni, M., Cauda, R., & Di Giambenedetto, S. (2014). Single tablet regimens are associated with reduced Efavirenz withdrawal in antiretroviral therapy naïve or switching for simplification HIV-infected patients. BMC Public Health, 14(1), 26-26. https://doi.org/10.1186/1471-2334-14-26

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abstract = "Efavirenz (EFV) administration is still controversial for its high rates of interruption mainly related to central nervous system side effects (CNS-SE). Aim of the study was to define if single tablet regimen (STR) as compared to bis-in-die (BID) or once-daily (OD) with ≥2 pills-a-day EFV formulations reduced the risk of interruption.",

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Fabbiani, M, Zaccarelli, M, Grima, P, Prosperi, M, Fanti, I, Colafigli, M, D'Avino, A, Mondi, A, Borghetti, A, Fantoni, M, Cauda, R & Di Giambenedetto, S 2014, 'Single tablet regimens are associated with reduced Efavirenz withdrawal in antiretroviral therapy naïve or switching for simplification HIV-infected patients', BMC Public Health, vol. 14, no. 1, pp. 26-26. https://doi.org/10.1186/1471-2334-14-26

TY - JOUR

T1 - Single tablet regimens are associated with reduced Efavirenz withdrawal in antiretroviral therapy naïve or switching for simplification HIV-infected patients

AU - Fabbiani, Massimiliano

AU - Zaccarelli, M

AU - Grima, Pierfrancesco

AU - Prosperi, M

AU - Fanti, Iuri

AU - Colafigli, Manuela

AU - D'Avino, Alessandro

AU - Mondi, Annalisa

AU - Borghetti, Alberto

AU - Fantoni, Massimo

AU - Cauda, Roberto

AU - Di Giambenedetto, Simona

PY - 2014

Y1 - 2014

N2 - Efavirenz (EFV) administration is still controversial for its high rates of interruption mainly related to central nervous system side effects (CNS-SE). Aim of the study was to define if single tablet regimen (STR) as compared to bis-in-die (BID) or once-daily (OD) with ≥2 pills-a-day EFV formulations reduced the risk of interruption.

AB - Efavirenz (EFV) administration is still controversial for its high rates of interruption mainly related to central nervous system side effects (CNS-SE). Aim of the study was to define if single tablet regimen (STR) as compared to bis-in-die (BID) or once-daily (OD) with ≥2 pills-a-day EFV formulations reduced the risk of interruption.

KW - Efavirenz

KW - antiretroviral

KW - nervous system

KW - therapy

KW - Efavirenz

KW - antiretroviral

KW - nervous system

KW - therapy

UR - https://publicatt.unicatt.it/handle/10807/50891

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U2 - 10.1186/1471-2334-14-26

DO - 10.1186/1471-2334-14-26

M3 - Article

SN - 1471-2458

VL - 14

SP - 26

EP - 26

JO - BMC Public Health

JF - BMC Public Health

IS - 1

ER -

Single tablet regimens are associated with reduced Efavirenz withdrawal in antiretroviral therapy naïve or switching for simplification HIV-infected patients

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

Keywords

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