Single tablet regimens are associated with reduced Efavirenz withdrawal in antiretroviral therapy naïve or switching for simplification HIV-infected patients

Massimo Fantoni, Roberto Cauda, Simona Di Giambenedetto, Massimiliano Fabbiani, Pierfrancesco Grima, Iuri Fanti, Manuela Colafigli, Alessandro D'Avino, Annalisa Mondi, Alberto Borghetti, Mauro Zaccarelli, Mattia Prosperi

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Efavirenz (EFV) administration is still controversial for its high rates of interruption mainly related to central nervous system side effects (CNS-SE). Aim of the study was to define if single tablet regimen (STR) as compared to bis-in-die (BID) or once-daily (OD) with ≥2 pills-a-day EFV formulations reduced the risk of interruption.
Original languageEnglish
Pages (from-to)26-26
Number of pages1
JournalBMC Public Health
Volume14
DOIs
Publication statusPublished - 2014

Keywords

  • Efavirenz
  • antiretroviral
  • nervous system
  • therapy

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