SFEMG in ocular myasthenia gravis diagnosis.

Luca Padua, Roberto Marra, Anna Paola Batocchi, Pietro Attilio Tonali

Research output: Contribution to journalArticle

102 Citations (Scopus)

Abstract

BACKGROUND AND OBJECTIVE: In typical cases, the patient's history and clinical examination make it possible to diagnose ocular myasthenia gravis (OMG). But, in many cases a clear clinical picture is not present and OMG diagnosis is very difficult because gold diagnostic standard tests are not available. The diagnostic tests for OMG are usually unable to display a good sensitivity and specificity simultaneously. In this paper, we studied 86 cases submitted for suspected OMG. METHODS: The patients were studied clinically and with various other tests used in OMG diagnosis (SFEMG, repetitive nerve stimulation, Ab anti AChR titration, tensilon test). RESULTS AND CONCLUSION: SFEMG showed the highest sensitivity (100%) while Ab anti AChR showed the highest specificity (100%). To our knowledge this is the largest population of suspected OMG studied using most of the diagnostic parameters, reported in the literature.
Original languageEnglish
Pages (from-to)1203-1207
Number of pages5
JournalClinical Neurophysiology
Volume111
Publication statusPublished - 2000

Keywords

  • Antiacetylcholine receptor antibody
  • Edrophonium
  • Neuromuscular transmission
  • Neurophysiology
  • Ocular myasthenia gravis
  • SFEMG

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