Severe acute hypertriglyeridemia during acute lymphoblastic leukemia induction successfully treated with plasmapheresis

Palma Maurizi, Vita Ridola, Paola Sabrina Buonuomo, Rossana Putzulu, Domenico Pietrini, Riccardo Riccardi

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Children suffering from Acute Lymphoblastic Leukaemia (ALL) treated with asparaginase and corticosteroids are at risk of developing severe lipid abnormalities. The authors report the case of a 10-year-old male with extremely high plasma triglyceride concentrations (4,000 mg/dl) during the induction phase of ALL associated with mild pancreatitis. Hypertriglyceridemia was successfully managed with plasmapheresis with a decrease in triglyceride levels to 590 mg/dl. Apheresis appears to be safe and effective in reducing hypertriglyceridemia and preventing related complications
Original languageEnglish
Pages (from-to)378-380
Number of pages3
JournalPEDIATRIC BLOOD & CANCER
Volume50
Publication statusPublished - 2006

Keywords

  • acute lymphoblastic leukemia
  • hypertriglyceridemia
  • plasmapheresis

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