Sequential treatment for Helicobacter pylori eradication in duodenal ulcer patients: improving the cost of pharmacotherapy

Cesare Hassan, V De Francesco, A Zullo, G Scaccianoce, D Piglionica, E Ierardi, C Panella, S. Morini

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Several studies have shown that Helicobacter pylori eradication rates with standard 7-day triple therapy are unsatisfactory. A novel 10-day sequential treatment regimen recently achieved a significantly higher eradication rate. To improve the pharmacotherapeutic cost, we evaluated whether an acceptable eradication rate could be achieved in peptic ulcer patients by halving the dose of clarithromycin.
Original languageEnglish
Pages (from-to)641-646
Number of pages6
JournalALIMENTARY PHARMACOLOGY & THERAPEUTICS
Volume18
Publication statusPublished - 2003
Externally publishedYes

Keywords

  • 2-Pyridinylmethylsulfinylbenzimidazoles
  • Adult
  • Aged
  • Amoxicillin
  • Antacids
  • Anti-Ulcer Agents
  • Benzimidazoles
  • Clarithromycin
  • Cost-Benefit Analysis
  • Drug Costs
  • Drug Therapy, Combination
  • Duodenal Ulcer
  • Female
  • Helicobacter Infections
  • Helicobacter pylori
  • Humans
  • Male
  • Middle Aged
  • Omeprazole
  • Prospective Studies
  • Tinidazole
  • Treatment Outcome

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