Sequential treatment for Helicobacter pylori eradication in duodenal ulcer patients: improving the cost of pharmacotherapy

Cesare Hassan; V De Francesco; A Zullo; G Scaccianoce; D Piglionica; E Ierardi; C Panella; S. Morini

Sequential treatment for Helicobacter pylori eradication in duodenal ulcer patients: improving the cost of pharmacotherapy

Cesare Hassan, V De Francesco, A Zullo, G Scaccianoce, D Piglionica, E Ierardi, C Panella, S. Morini

Research output: Contribution to journal › Article

Abstract

Several studies have shown that Helicobacter pylori eradication rates with standard 7-day triple therapy are unsatisfactory. A novel 10-day sequential treatment regimen recently achieved a significantly higher eradication rate. To improve the pharmacotherapeutic cost, we evaluated whether an acceptable eradication rate could be achieved in peptic ulcer patients by halving the dose of clarithromycin.

Original language	English
Pages (from-to)	641-646
Number of pages	6
Journal	ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Volume	18
Publication status	Published - 2003
Externally published	Yes

Keywords

2-Pyridinylmethylsulfinylbenzimidazoles
Adult
Aged
Amoxicillin
Antacids
Anti-Ulcer Agents
Benzimidazoles
Clarithromycin
Cost-Benefit Analysis
Drug Costs
Drug Therapy, Combination
Duodenal Ulcer
Female
Helicobacter Infections
Helicobacter pylori
Humans
Male
Middle Aged
Omeprazole
Prospective Studies
Tinidazole
Treatment Outcome

Cite this

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title = "Sequential treatment for Helicobacter pylori eradication in duodenal ulcer patients: improving the cost of pharmacotherapy",

abstract = "Several studies have shown that Helicobacter pylori eradication rates with standard 7-day triple therapy are unsatisfactory. A novel 10-day sequential treatment regimen recently achieved a significantly higher eradication rate. To improve the pharmacotherapeutic cost, we evaluated whether an acceptable eradication rate could be achieved in peptic ulcer patients by halving the dose of clarithromycin.",

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author = "Cesare Hassan and {De Francesco}, V and A Zullo and G Scaccianoce and D Piglionica and E Ierardi and C Panella and S. Morini",

year = "2003",

language = "English",

volume = "18",

pages = "641--646",

journal = "Alimentary Pharmacology and Therapeutics",

issn = "0269-2813",

publisher = "Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205",

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T1 - Sequential treatment for Helicobacter pylori eradication in duodenal ulcer patients: improving the cost of pharmacotherapy

AU - Hassan, Cesare

AU - De Francesco, V

AU - Zullo, A

AU - Scaccianoce, G

AU - Piglionica, D

AU - Ierardi, E

AU - Panella, C

AU - Morini, S.

PY - 2003

Y1 - 2003

N2 - Several studies have shown that Helicobacter pylori eradication rates with standard 7-day triple therapy are unsatisfactory. A novel 10-day sequential treatment regimen recently achieved a significantly higher eradication rate. To improve the pharmacotherapeutic cost, we evaluated whether an acceptable eradication rate could be achieved in peptic ulcer patients by halving the dose of clarithromycin.

AB - Several studies have shown that Helicobacter pylori eradication rates with standard 7-day triple therapy are unsatisfactory. A novel 10-day sequential treatment regimen recently achieved a significantly higher eradication rate. To improve the pharmacotherapeutic cost, we evaluated whether an acceptable eradication rate could be achieved in peptic ulcer patients by halving the dose of clarithromycin.

KW - 2-Pyridinylmethylsulfinylbenzimidazoles

KW - Adult

KW - Aged

KW - Amoxicillin

KW - Antacids

KW - Anti-Ulcer Agents

KW - Benzimidazoles

KW - Clarithromycin

KW - Cost-Benefit Analysis

KW - Drug Costs

KW - Drug Therapy, Combination

KW - Duodenal Ulcer

KW - Female

KW - Helicobacter Infections

KW - Helicobacter pylori

KW - Humans

KW - Male

KW - Middle Aged

KW - Omeprazole

KW - Prospective Studies

KW - Tinidazole

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KW - Aged

KW - Amoxicillin

KW - Antacids

KW - Anti-Ulcer Agents

KW - Benzimidazoles

KW - Clarithromycin

KW - Cost-Benefit Analysis

KW - Drug Costs

KW - Drug Therapy, Combination

KW - Duodenal Ulcer

KW - Female

KW - Helicobacter Infections

KW - Helicobacter pylori

KW - Humans

KW - Male

KW - Middle Aged

KW - Omeprazole

KW - Prospective Studies

KW - Tinidazole

KW - Treatment Outcome

UR - http://hdl.handle.net/10807/34669

M3 - Article

VL - 18

SP - 641

EP - 646

JO - Alimentary Pharmacology and Therapeutics

JF - Alimentary Pharmacology and Therapeutics

SN - 0269-2813

ER -

Sequential treatment for Helicobacter pylori eradication in duodenal ulcer patients: improving the cost of pharmacotherapy

Abstract

Keywords

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