Safety and efficacy of abobotulinumtoxinA for hemiparesis in adults with upper limb spasticity after stroke or traumatic brain injury: a double-blind randomised controlled trial

Research output: Contribution to journalArticle

101 Citations (Scopus)

Abstract

Resistance from antagonistic muscle groups might be a crucial factor reducing function in chronic hemiparesis. The resistance due to spastic co-contraction might be reduced by botulinum toxin injections. We assessed the effects of abobotulinumtoxinA injection in the upper limb muscles on muscle tone, spasticity, active movement, and function.
Original languageEnglish
Pages (from-to)992-1001
Number of pages10
JournalThe Lancet
Volume14
DOIs
Publication statusPublished - 2015

Keywords

  • Acetylcholine Release Inhibitors
  • Adult
  • Botulinum Toxins, Type A
  • Brain Injuries
  • Double-Blind Method
  • Female
  • Humans
  • Injections, Intramuscular
  • Male
  • Middle Aged
  • Muscle Spasticity
  • Paresis
  • Stroke
  • Treatment Outcome
  • Upper Extremity

Fingerprint

Dive into the research topics of 'Safety and efficacy of abobotulinumtoxinA for hemiparesis in adults with upper limb spasticity after stroke or traumatic brain injury: a double-blind randomised controlled trial'. Together they form a unique fingerprint.

Cite this