[Role of vaginal infection in fetal and neonatal mortality]

Translated title of the contribution: [Autom. eng. transl.] [Role of vaginal infection in fetal and neonatal mortality]

Giancarlo Paradisi, Laura Donati, Antonietta Labianca, Lorena Quagliozzi, Terryann Spagnuolo, Marina Bracaglia, Marta Nucci, Alessandro Caruso, A Di Vico

Research output: Contribution to journalArticle

Abstract

Preterm delivery is the chief problem in obstetrics today and the main determinant of infant mortality and morbidity. Despite the dramatic decrease in infant mortality rate during the past several years, the percentage of preterm (<37 weeks gestation) and low birth weight (LBW) (<2500) rates remain elevated. Approximately 10% of all births are preterm, with a rate of 1-2% of infant born before the end of the 32 weeks of gestation and with a weight <1500 g. Despite the importance of the problem, the majority of preterm live births remain unexplained, and programmatic attempts at reversing the high level of preterm births have not been successful. Numerous studies have linked bacterial vaginosis, chorioamniotitis and endometritis with preterm birth and LBW, especially among African women. The number of preterm live births among African women is twice the one among Caucasians. Bacterial vaginosis is an independent risk factor for preterm and LBW births and the mechanism by which bacterial vaginosis causes the preterm birth of an infant with LBW is unknown. The aim of this article was to underline the importance of the treatment and early identification of vaginal infection, in particular if due to bacterial vaginosis, as it can have a substantial affect on the incidence of preterm delivery with LBW.
Translated title of the contribution[Autom. eng. transl.] [Role of vaginal infection in fetal and neonatal mortality]
Original languageItalian
Pages (from-to)25-29
Number of pages5
JournalMinerva Ginecologica
Volume63
Publication statusPublished - 2011

Keywords

  • Female
  • Fetal Diseases
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases
  • Pregnancy
  • Pregnancy Complications, Infectious
  • Vaginosis, Bacterial

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