TY - JOUR
T1 - Right sinus of Valsalva aneurysm
AU - Farì, Giorgia
AU - Pennacchia, Ilaria
AU - Stigliano, Egidio
AU - Oliva, Antonio
AU - Carbone, Arnaldo
AU - Arena, Vincenzo
PY - 2020
Y1 - 2020
N2 - Aneurysms in the sinuses of Valsalva (SVA) are the least frequent and occur due to a weakness in the aortic wall that forms part of the sinus. This causes dilatation and the formation of a blind pocket in one of the aortic sinuses (usually he right sinus and less frequently the posterior one). It may be congenital or acquired: in a congenital SVA, the condition is frequently associated with Marfan's syndrome or other connective tissue disorders; instead, acquired forms of sinus of Valsalva aneurysm are associated with infections (syphilis, bacterial endocarditis, and tuberculosis), atherosclerosis and medial cystic necrosis, traumatic and degenerative diseases, abuse of drugs or alcoholism. Despite SVA is a well-known anomaly, autopsy images or reviews of the condition are very uncommon. Indeed we report here a fatal case of SVA in a 58-year-old homeless man found dead on the street. The autopsy, performed to determine the cause of death, releaved a massive aneurysm (in excess of 4 cm) involving the right coronary sinus of the aorta. In this case, the aneurysm may be an accidental finding: in effect we found no tromboses inside the aneurysm and the ostium was not obstructed, therefore the cause of death could be attribuited to fatal arrhythmia.
AB - Aneurysms in the sinuses of Valsalva (SVA) are the least frequent and occur due to a weakness in the aortic wall that forms part of the sinus. This causes dilatation and the formation of a blind pocket in one of the aortic sinuses (usually he right sinus and less frequently the posterior one). It may be congenital or acquired: in a congenital SVA, the condition is frequently associated with Marfan's syndrome or other connective tissue disorders; instead, acquired forms of sinus of Valsalva aneurysm are associated with infections (syphilis, bacterial endocarditis, and tuberculosis), atherosclerosis and medial cystic necrosis, traumatic and degenerative diseases, abuse of drugs or alcoholism. Despite SVA is a well-known anomaly, autopsy images or reviews of the condition are very uncommon. Indeed we report here a fatal case of SVA in a 58-year-old homeless man found dead on the street. The autopsy, performed to determine the cause of death, releaved a massive aneurysm (in excess of 4 cm) involving the right coronary sinus of the aorta. In this case, the aneurysm may be an accidental finding: in effect we found no tromboses inside the aneurysm and the ostium was not obstructed, therefore the cause of death could be attribuited to fatal arrhythmia.
KW - Aneurysm of right sinus of Valsalva
KW - Autopsy
KW - Cardiovascular disease
KW - Fatal arrhythmia
KW - Rare cardiac anomaly
KW - Aneurysm of right sinus of Valsalva
KW - Autopsy
KW - Cardiovascular disease
KW - Fatal arrhythmia
KW - Rare cardiac anomaly
UR - http://hdl.handle.net/10807/175499
U2 - 10.1016/j.carpath.2020.107209
DO - 10.1016/j.carpath.2020.107209
M3 - Article
SN - 1054-8807
VL - 47
SP - 107209-N/A
JO - Cardiovascular Pathology
JF - Cardiovascular Pathology
ER -