Reward-sensitivity, decisional bias and metacognitive deficits in cocaine drug addiction

Michela Balconi, Roberta Finocchiaro, Salvatore Campanella

Research output: Chapter in Book/Report/Conference proceedingConference contribution

31 Citations (Scopus)


The present research explored the effect of reward-sensitivity bias and metacognitive deficits in Substance Use Disorder (SUD) in decisional-making process. BAS (Behavioral Activation System) was considered as a predictive marker of dysfunctional behavior at IOWA. Secondly, we tried to relate this motivational system bias to some self-reported metacognitive measures (self-knowledge; strategic planning; flexibility; efficacy) in decisional processes. Thrirty-four SUD subjects (cocaine dependent) and thirthy-nine controls (CG) were submitted to IOWA task. SUD were associated with poorer performance on the IGT and dysfunctional metacognition ability (unrealistic representation). Reward-sensitivity (higher BAS, BAS-RR and BAS-D) increasing was observed in SUD more than CG, and it was found to be able to explain (regression analysis) the main behavioral deficits. More generally BAS-RR increasing may be considered as a predictive measure of a more risk-taking and dysfunctional behavior not only in pathological (SUD) subjects but also in subclinical sample (higher-BAS controls). The likely brain correlates (ventromedial prefrontal cortex, VMPFC, dysfunction) of this motivational and cognitive deficits were discussed.
Original languageEnglish
Title of host publicationAbstract Book of the "30th International Congress of Clinical Neurophysiology"
Number of pages1
Publication statusPublished - 2014
Event30th International Congress of Clinical Neurophysiology - Berlino
Duration: 20 Mar 201423 Mar 2014


Conference30th International Congress of Clinical Neurophysiology


  • Decision-making
  • Drug addiction
  • Iowa Gambling Task
  • Reward-sensitivity


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