Relationship and New Prospectives in Joint Hypermobility in Children with Autism Spectrum Disorder: Preliminary Data

Domenico Marco Maurizio Romeo, Marianna Moro, Mirko Pezone, Ilaria Venezia, Federica Mirra, Margherita De Biase, Agnese Polo, Ida Turrini, Maria Rosaria Lala, Chiara Velli, Francesca Sini, Domenico Dragone, Eugenio Maria Mercuri, Claudia Brogna

Research output: Contribution to journalArticle

Abstract

Autism spectrum disorder (ASD) and joint hypermobility (JH) are considered two different etiological and clinical entities that most often appear in childhood. Despite growing increased research showing a co-occurrence for both conditions, a link between them is rarely established in clinical settings, and the relationship between ASD and JH has not so far been completely investigated in all age groups of ASD children. This preliminary study examined a cohort of 67 non-syndromic ASD children aged 2–18 years (sex ratio M:F = 12:1) showing different degrees of cognitive impairment and autism severity, using the Beighton scale and its revised version. A total of 63% of ASD patients aged 2–4 years and 73% of ASD patients aged ≥5 years presented significant scores of hypermobility. No significant correlation was found comparing total laxity score and cognitive assessments and severity of autistic symptomatology (p > 0.05). The results suggest that JH could be considered as a clinical characteristic of ASD patients and it needs to be assessed in order to schedule a better rehabilitation program.
Original languageEnglish
Pages (from-to)1-10
Number of pages10
JournalJournal of Personalized Medicine
Volume13
DOIs
Publication statusPublished - 2023

Keywords

  • autism spectrum disorder
  • cognitive assessment
  • join hypermobility

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