Radiotherapy, local control and survival in brain tumors

Marco De Santis; Mario Balducci; L Basilico; L Marucci; G C Mattiucci; R M Niespolo; Daniela Smaniotto

Radiotherapy, local control and survival in brain tumors

Marco De Santis, Mario Balducci, L Basilico, L Marucci, G C Mattiucci, R M Niespolo, Daniela Smaniotto

Research output: Contribution to journal › Article

Abstract

High grade glial brain tumors and brain metastases are a complex subject with still unsatisfactory therapeutic results for the frequent absence of early and precise diagnosis as well as for the limited therapeutic interval between the tumor and presumed healthy tissues. The therapeutic problems of cellular hypoxia, the rapid recovery of sublethal damage for neoplastic cells, the rapid regrowth, have led to a number of efforts to deliver the dose of radiotherapy in various associations. The constant technological trend to increase the high dose gradient to the peripheral tumor, is reported. PMID: 9932472

Original language	English
Pages (from-to)	543-548
Number of pages	6
Journal	RAYS
Volume	23
Publication status	Published - 1998

Keywords

Brain Neoplasms
Dose Fractionation
Humans
Intraoperative Period
Neoplasm Recurrence, Local
Radiosurgery
Survival Rate

Cite this

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title = "Radiotherapy, local control and survival in brain tumors",

abstract = "High grade glial brain tumors and brain metastases are a complex subject with still unsatisfactory therapeutic results for the frequent absence of early and precise diagnosis as well as for the limited therapeutic interval between the tumor and presumed healthy tissues. The therapeutic problems of cellular hypoxia, the rapid recovery of sublethal damage for neoplastic cells, the rapid regrowth, have led to a number of efforts to deliver the dose of radiotherapy in various associations. The constant technological trend to increase the high dose gradient to the peripheral tumor, is reported. PMID: 9932472",

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pages = "543--548",

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issn = "0390-7740",

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TY - JOUR

T1 - Radiotherapy, local control and survival in brain tumors

AU - De Santis, Marco

AU - Balducci, Mario

AU - Basilico, L

AU - Marucci, L

AU - Mattiucci, G C

AU - Niespolo, R M

AU - Smaniotto, Daniela

PY - 1998

Y1 - 1998

N2 - High grade glial brain tumors and brain metastases are a complex subject with still unsatisfactory therapeutic results for the frequent absence of early and precise diagnosis as well as for the limited therapeutic interval between the tumor and presumed healthy tissues. The therapeutic problems of cellular hypoxia, the rapid recovery of sublethal damage for neoplastic cells, the rapid regrowth, have led to a number of efforts to deliver the dose of radiotherapy in various associations. The constant technological trend to increase the high dose gradient to the peripheral tumor, is reported. PMID: 9932472

AB - High grade glial brain tumors and brain metastases are a complex subject with still unsatisfactory therapeutic results for the frequent absence of early and precise diagnosis as well as for the limited therapeutic interval between the tumor and presumed healthy tissues. The therapeutic problems of cellular hypoxia, the rapid recovery of sublethal damage for neoplastic cells, the rapid regrowth, have led to a number of efforts to deliver the dose of radiotherapy in various associations. The constant technological trend to increase the high dose gradient to the peripheral tumor, is reported. PMID: 9932472

KW - Brain Neoplasms

KW - Dose Fractionation

KW - Humans

KW - Intraoperative Period

KW - Neoplasm Recurrence, Local

KW - Radiosurgery

KW - Survival Rate

KW - Brain Neoplasms

KW - Dose Fractionation

KW - Humans

KW - Intraoperative Period

KW - Neoplasm Recurrence, Local

KW - Radiosurgery

KW - Survival Rate

UR - http://hdl.handle.net/10807/114940

M3 - Article

SN - 0390-7740

VL - 23

SP - 543

EP - 548

JO - RAYS

JF - RAYS

ER -

Radiotherapy, local control and survival in brain tumors

Abstract

Keywords

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