Quality of life in patients with bladder cancer undergoing ileal conduit: A comparison of women versus men

Marco Racioppi, Pierfrancesco Bassi, Salvatore Siracusano, Carolina D’Elia, Maria Angela Cerruto, Omar Saleh, Sergio Serni, Mauro Gacci, Stefano Ciciliato, Alchiede Simonato, Antonio Porcaro, Vincenzo De Marco, Renato Talamini, Laura Toffoli, Francesco Visalli, Mauro Niero, Cristina Lonardi, Ciro Imbimbo, Paolo Verze, Vincenzo MironeMassimo Iafrate, Giovanni Cacciamani, Davide De Marchi, Walter Artibani

Research output: Contribution to journalArticle

4 Citations (Scopus)


Background/Aim: Studies comparing health-related quality of life (HR-QoL) between patients who underwent radical cystectomy (RC) and those who underwent a different form of urinary diversion has not reached yet univocal and reliable conclusions. The aim of our study was to evaluate bladder-specific long-term HR-QoL after radical cystectomy and ileal conduit. Patients and Methods: A multicenter study was carried out on 145 consecutive patients (112 males and 33 females) undergoing RC and ileal conduit (IC). HR-QoL assessment was conducted using Italian versions of European Organisation for Research and Treatment of Cancer QLQ-C30 and EORTC BLM-30 questionnaires. Results: Our data showed that women who underwent IC presented greater problems than men in cognitive functioning (mean score±SD: 77.3±27.9 vs. 87.8±18.6) as well in future perspective (score: 42.4±34.4 vs. 21.9±24.6). Nevertheless, men undergoing IC had more problems in sexual functioning than women (score: 23.3±24.5 vs. 7.0±20.3) (all p<0.05). Conclusion: In our series, female patients presented a greater burden than male patients in cognitive functioning as well in future perspective, but lower concerns with regard to sexual function.
Original languageEnglish
Pages (from-to)139-143
Number of pages5
JournalIn Vivo
Publication statusPublished - 2018


  • Biochemistry, Genetics and Molecular Biology (all)
  • Bladder cancer
  • Ileal conduit
  • Orthotopic neobladder
  • Pharmacology
  • Quality of life
  • Radical cystectomy


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