Pseudoexfoliation syndrome: In vivo confocal microscopy analysis

Gianluca Martone, Fabrizio Casprini, Claudio Traversi, Francesca Lepri, Patrizia Pichierri, Aldo Caporossi

Research output: Contribution to journalArticle

24 Citations (Scopus)


Pseudoexfoliation (PEX) syndrome is a common ocular disease that also affects the cornea. A case of clinical PEX syndrome, studied by in vivo corneal confocal microscopy is reported. The morphological analysis of the confocal images demonstrated hyper-reflective deposits and several dendritic cells in the basal epithelial layer. A fibrillar subepithelial structure was also found. The endothelial layer showed cell anomalies (polymegathism and pleomorphism) and hyper-reflective small endothelial deposits. Confocal microscopy is an in vivo imaging method that may provide new information on corneal alterations in PEX, and detect early corneal features. © 2007 The Authors; Journal compilation © 2007 Royal Australian and New Zealand College of Ophthalmologists.
Original languageEnglish
Pages (from-to)582-585
Number of pages4
JournalClinical and Experimental Ophthalmology
Publication statusPublished - 2007


  • Cell Count
  • Confocal microscopy
  • Corneal Diseases
  • Dendritic Cells
  • Endothelium, Corneal
  • Exfoliation Syndrome
  • HRT II
  • Humans
  • Keratopathy
  • Male
  • Microscopy, Confocal
  • Middle Aged
  • Ophthalmology
  • Pseudoexfoliation syndrome


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