Prognostic significance and clinical relevance of the expression of the HER family of type I receptor tyrosine kinases in human laryngeal squamous cell carcinoma

Giovanni Almadori, Maria Gabriella Ferrandina, Giovanni Scambia, Gaetano Paludetti, Francesco Bussu, Marco Gessi, Libero Lauriola, Franco Oreste Ranelletti

Research output: Contribution to journalArticlepeer-review

Abstract

The full clinical relevance of the expression pattern of HER family of type I receptor tyrosine kinases in laryngeal squamous cell carcinoma remains to be elucidated. We evaluated the clinical relevance of such parameter in our population.
Original languageEnglish
Pages (from-to)1144-1152
Number of pages9
JournalEuropean journal of cancer (Oxford, England : 1990)
Volume46
DOIs
Publication statusPublished - 2010

Keywords

  • Binding Sites
  • Carcinoma, Squamous Cell
  • Cell Line, Tumor
  • Epidermal Growth Factor
  • Female
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Immunohistochemistry
  • Laryngeal Neoplasms
  • Male
  • Middle Aged
  • Prognosis
  • Radioligand Assay
  • Receptor Protein-Tyrosine Kinases
  • Retrospective Studies
  • Tumor Markers, Biological

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