Processi di selezione del verbo e del nome in pazienti con malattia di Parkinson con differente prevalenza di lato

Translated title of the contribution: [Autom. eng. transl.] Verb and noun selection processes in Parkinson's disease patients with different side prevalence

Sonia Di Tella, Daniela Traficante, Maria Caterina Silveri, Francesca Baglio, Monia Cabinio, Raffaello Nemni

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

[Autom. eng. transl.] Patients with Parkinson's disease (PD) show a deficit in verb production as a possible expression of executive dysfunction in word selection processes. However, in a condition where the name must be selected from a greater number of alternatives than the verb, the production of the name becomes slower and less accurate. The left inferior frontal gyrus (GFIs) appears to be crucial in selection processes. In the present study we explore whether the ability in the selection processes of names and verbs is related to the cortical thickness of GFIs in patients with PD. Nine patients with right MP-left hemispheric damage (MPD-ES), 7 patients with left MP-right hemispheric damage (MPS-ED) and 16 healthy controls performed morphological tasks that differ in the number of alternatives to which the response should be selected : derive nouns from verbs (VN), ["observation" to "observe"] and generate verbs from names (NV) ["fail" from "failure"]. Accuracy and reaction times (TR) were recorded. The 32 subjects also received a structural MRI exam. The cortical thickness of the GFI was determined using FreeSurfer. In VN production, MPD-ES patients show lower accuracy than MPS-ED patients (58% vs. 74%). Furthermore, accuracy and TR correlate with GFI cortical thickness only in MPD-ES and only with GFIs, not only for the production of the name but also of the verb. The results suggest that the selection deficit emerges as a function of the difficulty of the task in the presence of a dysfunction of the GFIs, coherently with the hypothesis that the production of words requires to solve a competition between several alternatives. However, not only the request for executive resources, but also the linguistic nature of the stimuli is relevant in the selection processes. Executive resources and language interact in the GFIs in word selection processes and confirm the role of GFIs in linguistic production.
Translated title of the contribution[Autom. eng. transl.] Verb and noun selection processes in Parkinson's disease patients with different side prevalence
Original languageItalian
Title of host publicationAtti XI Convegno Nazionale di Psicologia dell’invecchiamento Milano, 25-26 Maggio 2018
Pages92
Number of pages1
Publication statusPublished - 2018
EventConvegno Nazionale di Psicologia dell’invecchiamento - Milano
Duration: 25 May 201826 May 2018

Conference

ConferenceConvegno Nazionale di Psicologia dell’invecchiamento
CityMilano
Period25/5/1826/5/18

Keywords

  • Disturbo di Parkinson
  • Giro Frontale Inferiore
  • processi di selezione delle parole
  • risonanza magnetica

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