Postpartum thyroiditis presenting as a cold nodule and evolving to Graves' disease

Salvatore Maria Corsello, Giampaolo Papi, S Corrado, C Carapezzi

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We describe the case of a 30-year-old woman who, five months after giving birth, was referred with a solitary nodule in her anterior neck. Laboratory analysis, ultrasonography, pertechnetate (Tc99m) thyroid scan and cytological examination of fine needle aspiration biopsy performed on the nodule led us to diagnose postpartum thyroiditis (PPT). Twenty-eight months after parturition, overt hyperthyroidism developed, with raised thyroperoxidase and thyroid stimulating hormone receptor antibody titres, diffuse high uptake of Tc99m at thyroid scan, and high vascular flow throughout the gland at Color-Power imaging. The diagnosis of Graves' disease (GD) was established. The differential diagnosis of thyrotoxicosis in the postpartum period, and the possible aetiological relationships between PPT and GD are discussed. To our knowledge, this is the first published report of a PPT presenting as a cold nodule, and evolving to GD.
Original languageEnglish
Pages (from-to)556-558
Number of pages3
JournalInternational Journal of Clinical Practice
Volume57
Publication statusPublished - 2003

Keywords

  • Adult
  • Biopsy, Needle
  • Diagnosis, Differential
  • Female
  • Graves Disease
  • Humans
  • Puerperal Disorders
  • Thyroid Nodule
  • Thyroiditis, Autoimmune
  • Thyrotoxicosis

Fingerprint Dive into the research topics of 'Postpartum thyroiditis presenting as a cold nodule and evolving to Graves' disease'. Together they form a unique fingerprint.

Cite this