Postoperative 5-FU based radiochemotherapy in rectal cancer: retrospective long term results and prognostic factors of a pooled analysis on 1,338 patients

Giovambattista Pani, Maria Antonietta Gambacorta, Vincenzo Valentini, Maria Cristina Barba, Vincenzo Fusco, Marco Di Nicola, Domenico Genovesi, Robert J. Myerson, Giampiero Ausili Cèfaro, Annamaria Vinciguerra, Antonietta Augurio, Marianna Trignani, Monica Di Tommaso, Marianna Nuzzo, Marco Lupattelli, Cynthia Aristei, Rita Bellavita, Luciano Scandolaro, Dorian Cosentino, Giuseppe PaniLuigi Ziccarelli, Ernesto Maranzano, Fabio Trippa, Piera Sciacero, Rita Niespolo, Cristina Leonardi, Tiziana Iannone, Maria Elena Rosetto, Piero Sanpaolo, Antonella Melano, Francesca Valvo, Carlo Capirci, Antonino De Paoli, Marta Di Nicola, Giovanna Mantello

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

To evaluate survival outcomes of patients in pStage II-III rectal cancer treated with adjuvant 5-fluorouracil-based radiochemotherapy and to retrospectively analyze the impact of prognostic variables on local control, metastasis-free survival and cause-specific survival.
Original languageEnglish
Pages (from-to)4557-4566
Number of pages10
JournalAnticancer Research
Volume33
Publication statusPublished - 2013

Keywords

  • Antimetabolites, Antineoplastic
  • Chemoradiotherapy
  • Disease-Free Survival
  • Fluorouracil
  • Humans
  • Kaplan-Meier Estimate
  • Lymphatic Metastasis
  • Postoperative Period
  • Prognosis
  • Rectal Neoplasms
  • Rectal cancer
  • Retrospective Studies
  • Treatment Outcome
  • adjuvant therapy
  • prognostic factors
  • staging

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