Pilot randomised experimental study evaluating isopropyl alcohol and UVC radiation in the disinfection of healthcare workers' smartphones

: Smartphones in medical settings pose infection risks due to harbouring pathogenic bacteria. This pilot study assesses the effectiveness duration of sanitisation methods, focusing on 70% isopropyl alcohol wipes and UVC boxes, aiming to obtain preliminary data on the reduction in Total Bacterial Load 3 hours post-sanitisation. A randomised monocentric trial with two intervention arms (wipes and UVC boxes) was designed. As participants, healthcare workers from three wards at Fondazione Policlinico Universitario "A. Gemelli" IRCCS Hospital were recruited, stratified by ward, and block randomised within each ward to control confounders. Seventy-one healthcare workers, mostly nurses (62%) were included in the study. Initial bacterial load reduction was significant with both disinfection techniques, but after 3 hours both methods showed increased bacterial levels, with wipes displaying potentially higher residual efficacy (p=0.056). To adequately size a trial (89% power, significance level 0.05) for assessing the residual efficacy of alcohol-impregnated wipes compared to UVC boxes at 3 hours post-sanitisation, 503 professionals per group were required. This study highlights the necessity for guidelines on hospital smartphone sanitisation and educational initiatives for healthcare workers and patients. Further studies, adequately sized, are necessary to determine optimal sanitisation intervals and assess pathogen transmission risks.