Phytochemical constituents and in vitro radical scavenging activity of different Aloe species

Luigi Lucini, Marco Pellizzoni, Gian Pietro Molinari, Roberto Pellegrino, Giuseppe Colla

Research output: Contribution to journalArticlepeer-review

67 Citations (Scopus)


The phytochemical profile of Aloe barbadensis Mill. and Aloe arborescens Mill. was investigated using colorimetric assays, triple quadrupole and time-of-flight mass spectrometry, focusing on phenolic secondary metabolites in the different leaf portions. Hydroxycinnamic acids, several characteristic anthrones and chromones, the phenolic dimer feralolide and flavonoids such as flavones and isoflavones were identified. The stable radical DPPH-test and the ORAC assay were then used to determine the in vitro radical scavenging. The outer green rind was the most active, while the inner parenchyma was much less effective. The 5-methylchromones aloesin, aloeresin A and aloesone were the most active among the pure secondary metabolites tested. The results suggest that several compounds are likely to contribute to the overall radical scavenging activity, and indicate that leaf portion must be taken into account when the plant is used for its antioxidant properties.
Original languageEnglish
Pages (from-to)501-507
Number of pages7
JournalFood Chemistry
Publication statusPublished - 2015


  • Aloe
  • Analytical Chemistry
  • Anthrones
  • Antioxidants
  • Chromatography, High Pressure Liquid
  • Chromones
  • Flavonoids
  • Food Science
  • Free Radical Scavengers
  • Glucosides
  • Mass Spectrometry
  • Medicine (all)
  • Metabolic profiling
  • ORAC
  • Phenylpropanoids
  • Plant Extracts
  • Plant Leaves
  • Polyphenols
  • Tandem Mass Spectrometry


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