Pertussis in infants less than 6 months of age and household contacts, Italy April 2014

Michela Sali, Teresa Spanu, Piero Valentini, Marilena La Sorda, Gabriele Buttinelli, Cecilia Fazio, Paola Vacca, Anna Carannante, Paola Stefanelli

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We report pertussis cases in 4 infants less than 6 months admitted with symptoms compatible with pertussis to the intensive care unit of the Università Cattolica del Sacro Cuore in Rome, April 2014. Realtime PCR confirmed pertussis diagnosis for the 4 infants, 2 of them were cousins, and for the household contacts of 1 of them. Analysis of pertussis toxin, its promoter and pertactin was also performed. First of all, this report emphasizes the need to investigate household contact of infants with pertussis; secondly, to evaluate the selective vaccination of household members of newborns as an effective programme to reduce pertussis in infants.
Original languageEnglish
Pages (from-to)1173-1174
Number of pages2
JournalHUMAN VACCINES & IMMUNOTHERAPEUTICS
DOIs
Publication statusPublished - 2015

Keywords

  • Italy
  • household contacts
  • infant
  • pertussis
  • vaccine

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