Abstract
We report pertussis cases in 4 infants less than 6 months admitted with symptoms compatible with pertussis to the intensive care unit of the Università Cattolica del Sacro Cuore in Rome, April 2014. Realtime PCR confirmed pertussis diagnosis for the 4 infants, 2 of them were cousins, and for the household contacts of 1 of them. Analysis of pertussis toxin, its promoter and pertactin was also performed. First of all, this report emphasizes the need to investigate household contact of infants with pertussis; secondly, to evaluate the selective vaccination of household members of newborns as an effective programme to reduce pertussis in infants.
Original language | English |
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Pages (from-to) | 1173-1174 |
Number of pages | 2 |
Journal | HUMAN VACCINES & IMMUNOTHERAPEUTICS |
DOIs | |
Publication status | Published - 2015 |
Keywords
- Italy
- household contacts
- infant
- pertussis
- vaccine