TY - JOUR
T1 - Penile cancer metastasizing to the breast: a case report
AU - Franceschini, Gianluca
AU - Sanchez, Alejandro Martin
AU - Di Leone, Alba
AU - Scaldaferri, Assunta
AU - Ferrucci, Massimo
AU - Mulè, Antonio
AU - Costantini, Melania
AU - Masetti, Riccardo
PY - 2016
Y1 - 2016
N2 - BACKGROUND:
Penile cancer is a relatively uncommon cancer in developed nations. Metastatic disease is rare, but lymphatic or vascular spreading has been previously reported to the liver, lungs, bones, brain, heart and skin.
CASE PRESENTATION:
We report a case of a 49-year-old white man with a penile squamous cell carcinoma previously treated with partial penectomy and bilateral inguinal lymph node dissection, followed by adjuvant therapy. Three years after treatment, the primitive neoplasm metastasized to the breast, presenting as a painful lump. Differentials of a secondary versus a malignant primary tumor were considered and in view of a diagnostic dilemma the lesion was excised.
CONCLUSIONS:
This case is unusual in its site of metastatic progression as well as in its pattern of clinical presentation. Awareness of such a condition by physicians is mandatory in order to make an early diagnosis and start prompt and correct therapeutic planning.
AB - BACKGROUND:
Penile cancer is a relatively uncommon cancer in developed nations. Metastatic disease is rare, but lymphatic or vascular spreading has been previously reported to the liver, lungs, bones, brain, heart and skin.
CASE PRESENTATION:
We report a case of a 49-year-old white man with a penile squamous cell carcinoma previously treated with partial penectomy and bilateral inguinal lymph node dissection, followed by adjuvant therapy. Three years after treatment, the primitive neoplasm metastasized to the breast, presenting as a painful lump. Differentials of a secondary versus a malignant primary tumor were considered and in view of a diagnostic dilemma the lesion was excised.
CONCLUSIONS:
This case is unusual in its site of metastatic progression as well as in its pattern of clinical presentation. Awareness of such a condition by physicians is mandatory in order to make an early diagnosis and start prompt and correct therapeutic planning.
KW - breast cancer
KW - treatment
KW - breast cancer
KW - treatment
UR - http://hdl.handle.net/10807/73514
U2 - 10.1186/s13256-016-0829-3
DO - 10.1186/s13256-016-0829-3
M3 - Article
SN - 1752-1947
VL - 10
SP - 53
EP - 56
JO - Journal of Medical Case Reports
JF - Journal of Medical Case Reports
ER -
