Patients with microvascular obstruction after primary percutaneous coronary intervention show a gp91phox (NOX2) mediated persistent oxidative stress after reperfusion

Giampaolo Niccoli, Andrea Celestini, Camilla Calvieri, Nicola Cosentino, Elena Falcioni, Roberto Carnevale, Cristina Nocella, Francesco Fracassi, Marco Roberto, Pasquale Pignatelli, Filippo Crea, Francesco Violi

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Persistent oxidative stress may play a key role in microvascular obstruction (MVO). We aimed at assessing the role of platelet gp91phox (NOX2), the catalytic subunit of NADPH oxidase in MVO.
Original languageEnglish
Pages (from-to)379-388
Number of pages10
JournalEUROPEAN HEART JOURNAL. ACUTE CARDIOVASCULAR CARE
Volume2
DOIs
Publication statusPublished - 2013

Keywords

  • ST-elevation myocardial infarction
  • microvascular obstruction
  • oxidative stress
  • primary percutaneous coronary intervention

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