Oral contraceptives, human papillomavirus and cervical cancer

Carlo La Vecchia, Stefania Boccia

Research output: Contribution to journalArticle

25 Citations (Scopus)


Oncogenic human papillomavirus is the key determinant of cervical cancer, but other risk factors interact with it to define individual risk. Among these, there is oral contraceptive (OC) use. A quantitative review of the link between OCs and cervical cancer was performed. Long-term (>5 year) current or recent OC use has been related to an about two-fold excess risk of cervical cancer. Such an excess risk, however, levels off after stopping use, and approaches unity 10 or more years after stopping. The public health implications of OC use for cervical cancer are limited. In any case, such implications are greater in middle-income and low-income countries, as well as in central and eastern Europe and Latin America, where cervical cancer screening and control remain inadequate.
Original languageEnglish
Pages (from-to)110-112
Number of pages3
JournalEuropean Journal of Cancer Prevention
Publication statusPublished - 2014


  • Gynecological Cancer
  • Oral contraceptives
  • cervical cancer
  • human papillomavirus


Dive into the research topics of 'Oral contraceptives, human papillomavirus and cervical cancer'. Together they form a unique fingerprint.

Cite this